Active Recombinant Mouse Il36g Protein, His-Tagged
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Cat.No. : | Il36g-01M Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant mouse Il36g Protein, His-tagged was expressed in E. coli cell |
Description : | The expression of IL-36γ is high in psoriatic plaques and in tissues including epithelial cells. Signaling of IL-36γ through the IL-1Rrp2 receptor, which is mainly expressed on certain dendritic cells. The interaction between the IL-36 ligands and IL-1Rrp2 receptor trigger dendritic cell maturation and activation. IL-36γ also work as an agonist of NF-κB, consequently, stimulate the inflammatory response in bronchial epithelial cells. |
Source : | Escherichia coli |
Species : | Mouse |
Tag : | His |
Form : | Lyophilized powder |
AA Sequence : | MGRETPDFGE VFDLDQQVWI FRNQALVTVP RSHRVTPVSV TILPCKYPES LEQDKGIAIY LGIQNPDKCL FCKEVNGHPT LLLKEEKILD LYHHPEPMKP FLFYHTRTGG TSTFESVAFP GHYIASSKTG NPIFLTSKKG EYYNINFNLD IKS with polyhistidine tag at the C-terminus |
Endotoxin : | <0.1 EU per 1 μg of the protein by the LAL method. |
Bio-activity : | Measure by its ability to induce IL-6 secretion in 3T3 cells. The ED50 for this effect is <15 ng/mL. The specific activity of recombinant mouse IL-36 gamma is > 6 x 10^4 IU/mg. |
Purity : | >98% as determined by SDS-PAGE. Ni-NTA chromatography |
Storage Buffer : | The protein was lyophilized from a solution containing 1X PBS, pH 7.4. |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. |
Storage : | Lyophilized protein should be stored at -20°C. Upon reconstitution, protein aliquots should be stored at -20°C or -80°C. |
Notes : | Please use within one month after protein reconstitution. |
Figure : |
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Gene Name : | Il36g interleukin 36G [ Mus musculus (house mouse) ] |
Official Symbol : | Il36g |
Synonyms : | If36g; Il1f9; IL-36gamma |
Gene ID : | 215257 |
mRNA Refseq : | NM_153511.3 |
Protein Refseq : | NP_705731.2 |
UniProt ID : | Q3U0P4 |
◆ Recombinant Protein
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IL36G-13H | Recombinant Human IL36G Protein, His-tagged | +Inquiry |
Il36g-176M | Recombinant Mouse Il36g Protein | +Inquiry |
IL36G-4844H | Recombinant Human IL36G protein, GST-tagged | +Inquiry |
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◆ Lysates
IL36G-5235HCL | Recombinant Human IL1F9 293 Cell Lysate | +Inquiry |
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IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b
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