Active Recombinant Mouse Il36g Protein, His-Tagged Il36g-01M

Active Recombinant Mouse Il36g Protein, His-Tagged

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Cat.No. : Il36g-01M Optional Service: Optional requirements on this protein
Product Overview : Recombinant mouse Il36g Protein, His-tagged was expressed in E. coli cell
Description : The expression of IL-36γ is high in psoriatic plaques and in tissues including epithelial cells. Signaling of IL-36γ through the IL-1Rrp2 receptor, which is mainly expressed on certain dendritic cells. The interaction between the IL-36 ligands and IL-1Rrp2 receptor trigger dendritic cell maturation and activation. IL-36γ also work as an agonist of NF-κB, consequently, stimulate the inflammatory response in bronchial epithelial cells.
Source : Escherichia coli
Species : Mouse
Tag : His
Form : Lyophilized powder
AA Sequence : MGRETPDFGE VFDLDQQVWI FRNQALVTVP RSHRVTPVSV TILPCKYPES LEQDKGIAIY LGIQNPDKCL FCKEVNGHPT LLLKEEKILD LYHHPEPMKP FLFYHTRTGG TSTFESVAFP GHYIASSKTG NPIFLTSKKG EYYNINFNLD IKS with polyhistidine tag at the C-terminus
Endotoxin : <0.1 EU per 1 μg of the protein by the LAL method.
Bio-activity : Measure by its ability to induce IL-6 secretion in 3T3 cells. The ED50 for this effect is <15 ng/mL. The specific activity of recombinant mouse IL-36 gamma is > 6 x 10^4 IU/mg.
Purity : >98% as determined by SDS-PAGE. Ni-NTA chromatography
Storage Buffer : The protein was lyophilized from a solution containing 1X PBS, pH 7.4.
Reconstitution : It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Storage : Lyophilized protein should be stored at -20°C. Upon reconstitution, protein aliquots should be stored at -20°C or -80°C.
Notes : Please use within one month after protein reconstitution.
Figure :

Gene Name : Il36g interleukin 36G [ Mus musculus (house mouse) ]
Official Symbol : Il36g
Synonyms : If36g; Il1f9; IL-36gamma
Gene ID : 215257
mRNA Refseq : NM_153511.3
Protein Refseq : NP_705731.2
UniProt ID : Q3U0P4
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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