Active Recombinant Mouse Interleukin 2 Receptor, Alpha Chain, His-tagged
Cat.No. : | Il2ra-5654M |
Product Overview : | RecombinantMouse Il2ra protein was expressed in Murine myeloma cellline.Glu22-Lys236, with a C-terminal 10-His tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Il2ra-5654M |
Description : | Il2ra isa 55 kDa type I membrane glycoprotein that belongs to the family of cytokinereceptors that utilize the common gamma chain subunit. Il2ra is primarilyexpressed on activated T cells and on regulatory T cells (Treg). The mouse Il2racDNA encodes a 268 amino acid (aa) precursor that includes a 21 aa signalpeptide, a 215 aa extracellular domain (ECD) with two Sushi domains, a 21 aatransmembrane segment, and an 11 aa cytoplasmic domain. Within the ECD, mouseIl2ra shares 81% and 58% aa sequence identity with rat and human Il2ra,respectively. |
Source : | Mammalian cells |
Form : | Lyophilizedfrom a 0.2 μm filtered solution in PBS. |
N-terminalSequence : | Glu22 |
MolecularWeight : | 26 kDa |
Activity : | Measuredby its ability to inhibit the IL-2-dependent proliferation of MO7e humanmegakaryocytic leukemic cells. The ED50 for this effect is typically 0.1-0.4μg/mL in the presence of 30 ng/mL of rhIL-2. |
Endotoxin Level : | <1.0EU per 1μg of the protein by the LAL method. |
SDS-PAGE : | 40-50kDa, reducing conditions. |
Purity : | >95%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Reconstitution : | 100 μg/mLin sterile PBS |
Storage : | Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3months, -20 to -70°C under sterile conditions after reconstitution. |
Gene Name : | Il2ra interleukin 2 receptor,alpha chain [ Mus musculus ] |
Official Symbol : | Il2ra |
Synonyms : | Il2ra; interleukin 2receptor, alpha chain; CD25; Il2r; Ly-43; interleukin-2receptor subunit alpha; IL2-RA; IL-2-RA; p55 chain; IL-2R alpha chain; IL-2Rsubunit alpha; IL-2 receptor subunit alpha; Interleukin-2 receptor alpha subunit |
Gene ID : | 16184 |
mRNA Refseq : | NM_008367 |
Protein Refseq : | NP_032393 |
UniProt ID : | Q544I2 |
Chromosome Location : | 2 |
Pathway : | Cytokine Signalingin Immune system; Cytokine-cytokine receptor interaction; Endocytosis; HTLV-Iinfection; Hematopoietic cell lineage; IL-2 Signaling Pathway; Immune System;Inflammatory Response Pathway; Interleukin receptor SHC signaling; Interleukin-2signaling; Interleukin-3, 5 and GM-CSF signaling; Jak-STAT signaling pathway;Measles; Signaling by Interleukins |
Function : | drug binding; interleukin-2binding; interleukin-2 receptor activity; protein binding; receptor activity |
Products Types
◆ Recombinant Protein | ||
IL2RA-2698R | Recombinant Rat IL2RA Protein, His (Fc)-Avi-tagged | +Inquiry |
IL2RA-319H | Recombinant Human IL2RA Protein, His-tagged | +Inquiry |
Il2ra-1676M | Recombinant Mouse Il2ra Protein, His-tagged | +Inquiry |
Il2ra-5704M | Active Recombinant Mouse Il2ra protein(Met1-Lys236), hFc-tagged | +Inquiry |
Il2ra-4513M | Recombinant Mouse Il2ra Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
IL2RA-2907HCL | Recombinant Human IL2RA cell lysate | +Inquiry |
IL2RA-1015CCL | Recombinant Cynomolgus IL2RA cell lysate | +Inquiry |
IL2RA-2024MCL | Recombinant Mouse IL2RA cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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