Recombinant Human IL2RA Protein (Met1-Gln240), C-His tagged
Cat.No. : | IL2RA-4270H |
Product Overview : | Recombinant human IL2RA (Met1-Gln240) fused with the C-terminal His tag was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | Interleukin-2 receptor subunit alpha (IL2RA) is also known as IL-2R subunit alpha, IL-2-RA, IL2-RA, TAC antigen, p55, CD antigen CD25, is a type I transmembrane glycoprotein. IL2RA is expressed on activated T cells and regulatory T cells, and is capable of binding IL2 with low affinity by itself. However, a ligand-induced high affinity heterotrimeric receptor complex is produced when IL2RA is associated non-covelently with the IL2 receptor beta and gamma chain, and subsequently initiates the intacellular signal pathways such as MAPK or JAK/STAT. On dendritic cells (DC), CD25 has been previously regarded as an activation marker, while both murine and human DC can express CD25, they do not express the beta-chain of the IL-2 receptor, which is indispensable for the execution of IL-2 signaling. |
Source : | Mammalian cells |
Species : | Human |
Tag : | C-His |
Form : | Lyophilized powder/frozen liquid |
Molecular Mass : | 27.20 kDa |
Protein Length : | Met1-Gln240 |
Endotoxin : | < 1.0 EU/μg of the protein as determined by the LAL method. |
Purity : | >90% as determined by SDS-PAGE. |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | Lyophilized from PBS, pH 7.4, 1mM EDTA, 4% trehalose, 1% mannitol. |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name : | IL2RA interleukin 2 receptor, alpha [ Homo sapiens (human) ] |
Official Symbol : | IL2RA |
Synonyms : | IL2RA; interleukin 2 receptor, alpha; IL2R; interleukin-2 receptor subunit alpha; CD25; p55; IL2-RA; IL-2-RA; TAC antigen; IL-2R subunit alpha; IL-2 receptor subunit alpha; TCGFR; IDDM10; |
Gene ID : | 3559 |
mRNA Refseq : | NM_000417 |
Protein Refseq : | NP_000408 |
MIM : | 147730 |
UniProt ID : | P01589 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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