Active Recombinant Mouse Pf4 Protein

• Cat.No.: Pf4-4803M
• Product Overview: Purified recombinant protein of Mouse platelet factor 4 (Pf4 / PF-4) without tag was expressed in E. coli.

Specification

• Species: Mouse
• Source: E.coli
• Protein Length: Val30-Ser105
• Description: Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation.
• Bio-activity: The ED50 is 3-5 μg/ml, corresponding to a specific activity 2.0-3.3 × 10^2 units/mg, determined by a dose-dependent inhibition of human FGF-basic-dependent proliferation of human umbilical vein endothelial cells (HUVEC).
• Molecular Mass: 8.2 kDa
• Endotoxin: Less than 0.01 ng/μg protein as determined by the LAL method
• Purity: > 98%, as determined by Coomassie stained SDS-PAGE.
• Stability: Stable for at least 6 months from date of receipt under proper storage and handling conditions.
• Storage: Store at -80 centigrade.
• Concentration: Protein formulated and vialed at >50 μg/mL in specified buffer
• Storage Buffer: 1 x PBS

Gene Information

• Gene Name: Pf4 platelet factor 4 [ Mus musculus (house mouse) ]
• Official Symbol: Pf4
• Synonyms: PF4; platelet factor 4; PF-4; C-X-C motif chemokine 4; chemokine (C-X-C motif) ligand 4; Cxcl4; Scyb4
• Gene ID: 56744
• mRNA Refseq: NM_019932
• Protein Refseq: NP_064316
• UniProt ID: Q9Z126