Active Recombinant Mouse VCAM1, MIgG2a Fc-tagged

• Cat.No.: VCAM1-1793M
• Product Overview: The extracellular domain of mouse VCAM-1 (NP_035823.3) (Lys26-Glu698) is fused to the N-terminus of the Fc region of mouse IgG2a was expressed in CHO cell.

Specification

• Species: Mouse
• Source: CHO
• Tag: Fc
• Description: This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed bycytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion andsignal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Threealternatively spliced transcripts encoding different isoforms have been described for this gene
• Form: Lyophilized from 0.2μm-filtered solution in PBS.
• Bio-activity: Measured by the ability of the immobilized protein to support the adhesion of U937 human histiocytic lymphoma cells.
• Molecular Mass: 100KDa (monomer)
• AA Sequence: Lys26-Glu698
• Endotoxin: <0.06 eu/μg="" as="" determined="" by="" lal="">
• Purity: >98%, by SDS-PAGE under reducing conditions.
• Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
• Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
• Warning: Avoid freeze/thaw cycles.

Gene Information

• Gene Name: Vcam1 vascular cell adhesion molecule 1 [ Mus musculus ]
• Official Symbol: VCAM1
• Synonyms: VCAM1; vascular cell adhesion molecule 1; vascular cell adhesion protein 1; V-CAM 1; CD106; Vcam-1
• Gene ID: 22329
• mRNA Refseq: NM_011693
• Protein Refseq: NP_035823
• Pathway: Adaptive Immune System, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem
• Function: cell adhesion molecule binding; integrin binding