Active Recombinant Mouse VCAM1, MIgG2a Fc-tagged

Cat.No. : VCAM1-1793M
Product Overview : The extracellular domain of mouse VCAM-1 (NP_035823.3) (Lys26-Glu698) is fused to the N-terminus of the Fc region of mouse IgG2a was expressed in CHO cell.
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Description : This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed bycytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion andsignal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Threealternatively spliced transcripts encoding different isoforms have been described for this gene
Source : CHO cell
Species : Mouse
Tag : MIgG2a Fc-tagged
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : Measured by the ability of the immobilized protein to support the adhesion of U937 human histiocytic lymphoma cells.
Molecular Mass : 100KDa (monomer)
AA Sequence : Lys26-Glu698
Endotoxin : <0.06 eu/μg as determined by lal>
Purity : >98%, by SDS-PAGE under reducing conditions.
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Warning : Avoid freeze/thaw cycles.
Gene Name : Vcam1 vascular cell adhesion molecule 1 [ Mus musculus ]
Official Symbol : VCAM1
Synonyms : VCAM1; vascular cell adhesion molecule 1; vascular cell adhesion protein 1; V-CAM 1; CD106; Vcam-1;
Gene ID : 22329
mRNA Refseq : NM_011693
Protein Refseq : NP_035823
Pathway : Adaptive Immune System, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem;
Function : cell adhesion molecule binding; integrin binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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