Active Recombinant Rat Camkk1, GST-tagged
Cat.No. : | Camkk1-106R |
Product Overview : | Recombinant full-length rat CAMKK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | CAMKK1 or CAMKKalpha is a Ca(2+)/calmodulin-dependent protein kinase that activates CAM-kinases I and IV via phosphorylation of their Thr(177) and Thr(196) residues, respectively. Recent studies have shown that the activity of CAMKK1 is decreased upon phosphorylation by cAMP-dependent protein kinase (PKA) The CAMKKalpha has been identified in intact cells as AMPKKs, predicting a significant role for this kinase in regulating AMPK activity in vivo. It has been shown that 2-deoxyglucose- and ionomycin-stimulated AMPK activity is substantially reduced in HeLa cells transfected with small interfering RNAs specific for CAMKKalpha. |
Source : | Sf9 insect cells using baculovirus |
Species : | Rat |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | The specific activity of CAMKK1 was determined to be 9 nmol /min/mg |
Molecular Mass : | ~88 kDa |
Purity : | >85% by densitometry |
Applications : | Kinase Assay, Western Blot |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1 μg/μl |
Gene Name : | Camkk1 calcium/calmodulin-dependent protein kinase kinase 1, alpha [ Rattus norvegicus ] |
Official Symbol : | Camkk1 |
Synonyms : | CAMKK1; calcium/calmodulin-dependent protein kinase kinase 1, alpha; calcium/calmodulin-dependent protein kinase kinase 1; caMKK 1; caM-KK 1; alpha CaMKK; caMKK alpha; caM-KK alpha; caM-kinase kinase 1; caM-kinase IV kinase; caM-kinase kinase alpha; calcium/calmodulin-dependent protein kinase kinase alpha; |
Gene ID : | 60341 |
mRNA Refseq : | NM_031662 |
Protein Refseq : | NP_113850 |
Pathway : | Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; |
Function : | ATP binding; calmodulin binding; calmodulin-dependent protein kinase activity; calmodulin-dependent protein kinase activity; nucleotide binding; protein serine/threonine kinase activity; protein serine/threonine kinase activity; |
Products Types
◆ Recombinant Protein | ||
CAMKK1-0171H | Recombinant Human CAMKK1 Protein (M1-S505), Tag Free | +Inquiry |
Camkk1-1946M | Recombinant Mouse Camkk1 Protein, Myc/DDK-tagged | +Inquiry |
CAMKK1-415H | Recombinant Human CAMKK1 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
CAMKK1-0339H | Recombinant Human CAMKK1 Protein, GST-Tagged | +Inquiry |
CAMKK1-771R | Recombinant Rat CAMKK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CAMKK1-7873HCL | Recombinant Human CAMKK1 293 Cell Lysate | +Inquiry |
CAMKK1-7874HCL | Recombinant Human CAMKK1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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