Active Recombinant Rat Kitlg

• Cat.No.: Kitlg-63R
• Product Overview: Recombinant rat SCF is an 18.4 kDa polypeptide containing 165 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF.

Specification

• Species: Rat
• Source: E.coli
• Tag: Non
• Description: soluble growth factor that activates c-kit tyrosine kinase receptor; important for signaling in spermatogenesis; putative regulator of Leydig cell development.
• Bio-activity: Determined by the dose-dependent stimulation of the proliferation of the human TF-1 cells. The expected ED50 for this effect is 20 - 40 ng/ml.
• Molecular Mass: 18.4 kDa
• AA Sequence: MQEICRNPVT DNVKDITKLV ANLPNDYMIT LNYVAGMDVL PSHCWLRDMV THLSVSLTTL LDKFSNISEG LSNYSIIDKL GKIVDDLVAC MEENAPKNVK ESLKKPETRN FTPEEFFSIF NRSIDAFKDF MVASDTSDCV LSSTLGPEKD SRVSVTKPFM LPPVA
• Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.

Gene Information

• Gene Name: Kitlg KIT ligand [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Kitlg
• Synonyms: Kitlg; Mgf; SCF; Kitl; KIT ligand; kit ligand; C-kit ligand; stem cell factor KL-1; mast cell growth factor; steel factor/kit ligand; hematopoietic growth factor KL
• Gene ID: 60427
• mRNA Refseq: NM_021843
• Protein Refseq: NP_068615
• UniProt ID: P21581
• Chromosome Location: 7q13
• Pathway: Adaptive Immune System; Cytokine-cytokine receptor interaction; DAP12 interactions
• Function: cytokine activity; growth factor activity; stem cell factor receptor binding