CD25 protein-coupled magnetic MicroBeads
| Cat.No. : | CD25-693M |
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| Species : | Mouse |
| Capacity : | for 1×10^9 total cells |
| Background : | For separation, CD25+ cells are indirectly magnetically labeled with CD25-PE and Anti-PE MicroBeads. CD25 is the IL-2R α-chain, which combined with the β-chain (CD122) and the γ-chain (CD132) forms the functional IL-2R complex. Binding of CD25-PE does not inhibit the adhesion of IL-2 to its receptor. IL-2Rα is expressed on activated T and B cells, to a lower extent on activated dendritic cells, on regulatory T cells, in the early stage of thymic T cell development (CD4-CD8-), and transiently during B cell ontogeny. NK cells and naive T and B cells do not express IL2-Rα. |
| Application : | CD25+ cells isolated by using the CD25 MicroBead Kit are suitable for in vitro analysis, coculture experiments, or adoptive transfer. |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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