Recombinant Human General Transcription Factor IIA, 2, 12kDa, T7-tagged GTF2A2-3000H

Recombinant Human General Transcription Factor IIA, 2, 12kDa, T7-tagged

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Recombinant Human General Transcription Factor IIA, 2, 12kDa, T7-tagged

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Cat. No. : GTF2A2-3000H
Product Overview : Recombinant Human GTF2A2 protein was expressed in E.coli with T7-tag at the N-terminus. The molecular weight is 12457 Da (109 aa).
Description : General transcription factor IIA, 2, 12kDa is a nuclear protein involved in the RNA polymerase II-dependent transcription of DNA. GTF2A2 is one of several general (basal) transcription factors (GTFs) that are required for all transcription events that use RNA polymerase II. Other GTFs include TFIID, a complex composed of the TATA binding protein TBP and TBP-associated factors (TAFs), as well as the factors TFIIB, TFIIE, TFIIF, and TFIIH. Together, these factors are responsible for promoter recognition and the formation of a transcription preinitiation complex (PIC) capable of initiating RNA synthesis from a DNA template.
Sequences of amino acids : 1-109 aa
Formulation : 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3.
Purity : 95%
Gene Name : GTF2A2 general transcription factor IIA, 2, 12kDa [ Homo sapiens ]
Synonyms : TF2A2; TFIIA; HsT18745; GTF2A2; transcription initiation factor IIA subunit 2; TFIIAS; TFIIA-12; TFIIA-gamma; TFIIA p12 subunit; OTTHUMP00000196512; general transcription factor IIA subunit 2; transcription initiation factor IIA gamma chain
Gene ID : 2958
mRNA Refseq : NM_004492
Protein Refseq : NP_004483
MIM : 600519
UniProt ID : P52657
Chromosome Location : 15q22.2
Pathway : Basal transcription factors; Gene Expression; HIV Infection; Transcription
Function : RNA polymerase II transcription factor activity; TATA-binding protein binding; general RNA polymerase II transcription factor activity; contributes_to general RNA polymerase II transcription factor activity; identical protein binding; protein binding; protein heterodimerization activity; protein homodimerization activity; transcription coactivator activity; transcription factor binding

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