"GTF2A2" Related Products

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Recombinant Human General Transcription Factor IIA, 2, 12kDa, T7-tagged

Cat. No.: GTF2A2-3000H
Product Overview: Recombinant Human GTF2A2 protein was expressed in E.coli with T7-tag at the N-terminus. The molecular weight is 12457 Da (109 aa).
Description: General transcription factor IIA, 2, 12kDa is a nuclear protein involved in the RNA polymerase II-dependent transcription of DNA. GTF2A2 is one of several general (basal) transcription factors (GTFs) that are required for all transcription events that use RNA polymerase II. Other GTFs include TFIID, a complex composed of the TATA binding protein TBP and TBP-associated factors (TAFs), as well as the factors TFIIB, TFIIE, TFIIF, and TFIIH. Together, these factors are responsible for promoter recognition and the formation of a transcription preinitiation complex (PIC) capable of initiating RNA synthesis from a DNA template.
Sequences of amino acids: 1-109 aa
Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3.
Purity: 95%
Gene Name: GTF2A2 general transcription factor IIA, 2, 12kDa [ Homo sapiens ]
Synonyms: TF2A2; TFIIA; HsT18745; GTF2A2; transcription initiation factor IIA subunit 2; TFIIAS; TFIIA-12; TFIIA-gamma; TFIIA p12 subunit; OTTHUMP00000196512; general transcription factor IIA subunit 2; transcription initiation factor IIA gamma chain
Gene ID: 2958
mRNA Refseq: NM_004492
Protein Refseq: NP_004483
MIM: 600519
UniProt ID: P52657
Chromosome Location: 15q22.2
Pathway: Basal transcription factors; Gene Expression; HIV Infection; Transcription
Function: RNA polymerase II transcription factor activity; TATA-binding protein binding; general RNA polymerase II transcription factor activity; contributes_to general RNA polymerase II transcription factor activity; identical protein binding; protein binding; protein heterodimerization activity; protein homodimerization activity; transcription coactivator activity; transcription factor binding

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