"ATG5" Related Products

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Recombinant Human ATG5, His-tagged

Cat. No.: ATG5-3425H
Product Overview: Recombinant human ATG5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description: Autophagy protein 5, also known as ATG5, belongs to the autophagy-related (ATG) genes family. Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents. ATG5 protein is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form autophagosomes. ATG5 also plays an important role in the apoptotic process. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 40% glycerol, 0.2M NaCl
Molecular Weight: 34.6 kDa (295aa), confirmed by MALDI-TOF
Purity: > 85% by SDS - PAGE
Concentration: 0.25 mg/ml (determined by Bradford assay)
Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MTDDKDVLRD VWFGRIPTCF TLYQDEITER EAEPYYLLLPRVSYLTLVTD KVKKHFQKVM RQEDISEIWF EYEGTPLKWH YPIGLLFDLL ASSSALPWNITVHFKSFPEK DLLHCPSKDA IEAHFMSCMK EADALKHKSQ VINEMQKKDH KQLWMGLQND RFDQFWAINR KLMEYPAEEN GFRYIPFRIY QTTTERPFIQ KLFRPVAADG QLHTLGDLLKEVCPSAIDPE DGEKKNQVMI HGIEPMLETP LQWLSEHLSY PDNFLHISII PQPTD
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: ATG5 ATG5 autophagy related 5 homolog (S. cerevisiae) [ Homo sapiens ]
Synonyms: ATG5; ATG5 autophagy related 5 homolog (S. cerevisiae); ASP; APG5L; hAPG5; APG5-LIKE; APG5 (autophagy 5, S. cerevisiae)-like; APG5 autophagy 5-like (S. cerevisiae); Autophagy protein 5; APG5-like Apoptosis-specific protein; OTTHUMP0000 0017823; OTTHUMP00000017824; OTTHUM P00000040507; apoptosis specific protein
Gene ID: 9474
mRNA Refseq: NM_004849
Protein Refseq: NP_004840
MIM: 604261
UniProt ID: Q9H1Y0
Chromosome Location: 6q21
Pathway: RIG-I-like receptor signaling pathway; Regulation of autophagy
Function: protein binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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