Recombinant Mouse S100 Calcium Binding Protein A8 (calgranulin A), His-tagged S100a8-5107M

Recombinant Mouse S100 Calcium Binding Protein A8 (calgranulin A), His-tagged

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Recombinant Mouse S100 Calcium Binding Protein A8 (calgranulin A), His-tagged

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Cat. No. : S100a8-5107M
Product Overview : Recombinant mouseS100a8 protein, fused to His-tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography.
Description : S100a8, also knownMRP8, is a member of the S100 family, EF-hand superfamily of calcium bindingproteins. This protein is localized in the cytoplasm and/or nucleus of a widerange of cells, and involved in the regulation of a number of cellularprocesses such as cell cycle progression and differentiation. It functionsboth intracellularly and extracellularly, where it binds to RAGE and CD36.Altered expression of this protein is associated with the disease cysticfibrosis.
Concentration : 1 mg/ml
Source : Mouse
Host : E.coli
Form : Suppliedas a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 30% glycerol, 0.1MNaCl and 1mM DTT.
Purity : > 95% by SDS -PAGE
Sequence : 1-89 amino acids:MGSSHHHHHH SSGLVPRGSH MPSELEKALS NLIDVYHNYS NIQGNHHALY KNDFKKMVTT ECPQFVQNINIENLFRELDI NSDNAINFEE FLAMVIKVGV ASHKDSHKE
Molecular Mass : 12.4 kDa(109aa), confirmed by MALDI-TOF.
Applications : SDS-PAGE
Storage : Storeat 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg Cor - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
OfficialSymbol : S100a8
Protein S100A8 PDB 1mr8. :

Publication : Myeloid-related protein 8 induces self-tolerance and cross-tolerance to bacterial infection via TLR4-and TLR2-mediated signal pathways.
Gene Name : S100a8 S100 calcium bindingprotein A8 (calgranulin A) [ Mus musculus ]
Synonyms : S100a8;S100 calcium binding protein A8 (calgranulin A); p8; B8Ag;CFAg; Caga; MRP8; CP-10; 60B8Ag; AI323541; protein S100-A8; MRP-8;calgranulin-A; chemotactic S100 protein; chemotactic cytokine CP-10;pro-inflammatory S100 cytokine; S100 calcium-binding protein A8; leukocyte L1complex light chain; migration inhibitory factor-related protein 8; Protein S100-A8; Calgranulin-A; Chemotactic cytokine CP-10; Leukocyte L1complex light chain; Migration inhibitory factor-related protein 8; Pro-inflammatoryS100 cytokine
Gene ID : 20201
mRNA Refseq : NM_013650
Protein Refseq : NP_038678
UniProt ID : P27005
Chromosome Location : 39.9 cM
Function : calcium ion binding

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