Recombinant Human Delta-Like 1 (Drosophila)

• Cat.No.: DLL1-4993H
• Product Overview: Recombinant human DLL1was expressed in 293T cells and purified by using SDS PAGE and HPLC.

Specification

• Cat. No.: DLL1-4993H
• Description: Human sDLL-1comprises the extracellular signaling domain of DLL1, a member of astructurally-related family of single-pass type I trans-membrane proteinsthat serve as ligands for Notch receptors. It is expressed in the heart andpancreas, and to a lesser extent in various other tissues. DLL-1 functions tospecifically activate the Notch-1 and Notch-2 receptors.
• Source: Human
• Host: 293T cells
• Form: Lyophilizedfrom PBS, pH 7.5
• Purity: >95% pure by SDSPAGE and HPLC
• Sequence: Region of SDLL1protein corresponding to amino acids SGVFELKLQE FVNKKGLLGN RNCCRGGAGP PPCACRTFFRVCLKHYQASV SPEPPCTYGS AVTPVLGVDS FSLPDGGGAD SAFSNPIRFP FGFTWPGTFS LIIEALHTDSPDDLATENPE RLISRLATQR HLTVGEEWSQ DLHSSGRTDL KYSYRFVCDE HYYGEGCSVF CRPRDDAFGHFTCG
• Molecular Mass: 57-60 kDa
• Applications: Numerousapplications are possible with this product and should be tested by the enduser under their own laboratory conditions
• Storage: Storeat 4 deg C until reconstitution. Following reconstitution aliquot and freezeat -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
• OfficialSymbol: DLL1

Gene Information

• Gene Name: DLL1 delta-like 1 (Drosophila)[ Homo sapiens ]
• Synonyms: DLL1; delta-like 1 (Drosophila); DL1; Delta; DELTA1; delta-likeprotein 1; H-Delta-1; OTTHUMP00000017690; drosophila Delta homolog 1;Drosophila Delta homolog 1; delta (Drosophila)-like 1; Delta1
• Gene ID: 28514
• mRNA Refseq: NM_005618
• Protein Refseq: NP_005609
• MIM: 606582
• UniProt ID: O00548
• Chromosome Location: 6q27
• Pathway: Delta-NotchSignaling Pathway; Notch receptor binds with a ligand; Notch signalingpathway; Presenilin action in Notch and Wnt signaling; Receptor-ligandbinding initiates the second proteolytic cleavage of Notch receptor;Signaling by Notch
• Function: Notchbinding; calcium ion binding; protein binding