Recombinant Human Delta-Like 1 (Drosophila) DLL1-4993H

Recombinant Human Delta-Like 1 (Drosophila)

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Recombinant Human Delta-Like 1 (Drosophila)

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Cat. No. : DLL1-4993H
Product Overview : Recombinant human DLL1was expressed in 293T cells and purified by using SDS PAGE and HPLC.
Description : Human sDLL-1comprises the extracellular signaling domain of DLL1, a member of astructurally-related family of single-pass type I trans-membrane proteinsthat serve as ligands for Notch receptors. It is expressed in the heart andpancreas, and to a lesser extent in various other tissues. DLL-1 functions tospecifically activate the Notch-1 and Notch-2 receptors.
Source : Human
Host : 293T cells
Form : Lyophilizedfrom PBS, pH 7.5
Purity : >95% pure by SDSPAGE and HPLC
Sequence : Region of SDLL1protein corresponding to amino acids SGVFELKLQE FVNKKGLLGN RNCCRGGAGP PPCACRTFFRVCLKHYQASV SPEPPCTYGS AVTPVLGVDS FSLPDGGGAD SAFSNPIRFP FGFTWPGTFS LIIEALHTDSPDDLATENPE RLISRLATQR HLTVGEEWSQ DLHSSGRTDL KYSYRFVCDE HYYGEGCSVF CRPRDDAFGHFTCG
Molecular Mass : 57-60 kDa
Applications : Numerousapplications are possible with this product and should be tested by the enduser under their own laboratory conditions
Storage : Storeat 4 deg C until reconstitution. Following reconstitution aliquot and freezeat -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
OfficialSymbol : DLL1
Gene Name : DLL1 delta-like 1 (Drosophila)[ Homo sapiens ]
Synonyms : DLL1; delta-like 1 (Drosophila); DL1; Delta; DELTA1; delta-likeprotein 1; H-Delta-1; OTTHUMP00000017690; drosophila Delta homolog 1;Drosophila Delta homolog 1; delta (Drosophila)-like 1; Delta1
Gene ID : 28514
mRNA Refseq : NM_005618
Protein Refseq : NP_005609
MIM : 606582
UniProt ID : O00548
Chromosome Location : 6q27
Pathway : Delta-NotchSignaling Pathway; Notch receptor binds with a ligand; Notch signalingpathway; Presenilin action in Notch and Wnt signaling; Receptor-ligandbinding initiates the second proteolytic cleavage of Notch receptor;Signaling by Notch
Function : Notchbinding; calcium ion binding; protein binding

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