Recombinant Human Cell Division Cycle 26 Homolog (S. cerevisiae), His-tagged
Cat.No. : | CDC26-1678H |
Product Overview : | Recombinant humanCDC26 protein, fused to His-tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography. |
- Specification
- Gene Information
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Cat. No. : | CDC26-1678H |
Description : | CDC26, also known asANAPC12, APC12, belongs to the CDC26 family which orchestrates progressionthrough mitosis by decorating cell-cycle regulators with ubiquitin chains.This protein is component of the anaphase promoting complex/cyclosome(APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progressionthrough mitosis and the G1 phase of the cell cycle. The APC/C complex acts bymediating ubiquitination and subsequent degradation of target proteins. |
Concentration : | 1 mg/ml |
Source : | Human |
Host : | E. coli |
Form : | Suppliedas a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 40% glycerol and 0.1M NaCl. |
Purity : | > 90% by SDS-PAGE |
Sequence : | 1-85 amino acids:MGSSHHHHHH SSGLVPRGSH MLRRKPTRLE LKLDDIEEFE NIRKDLETRK KQKEDVEVVG GSDGEGAIGLSSDPKSREQM INDRIGYKPQ PKPNNRSSQF GSLEF |
Molecular Mass : | 11.9 kDa (105 aa),confirmed by MALDI-TOF. |
Applications : | SDS-PAGE |
Storage : | Store at 4 deg C forshort term storage (1/2 weeks). Aliquot and store at -20 deg C or -70 deg Cfor long term storage. Avoid repeated freeze/thaw cycles. |
OfficialSymbol : | CDC26 |
Gene Name : | CDC26 cell division cycle 26homolog (S. cerevisiae) [ Homo sapiens ] |
Synonyms : | CDC26; cell divisioncycle 26 homolog (S. cerevisiae); APC12; ANAPC12; C9orf17; anaphase-promotingcomplex subunit CDC26; OTTHUMP00000021952; anaphase promoting complex subunit12; anaphase-promoting complex subunit 12; cell division cycle protein 26homolog; CDC26 subunit of anaphase promoting complex; cell division cycle 26;chromosome 9 open reading frame 17; Anaphase-promoting complex subunit 12 |
Gene ID : | 246184 |
mRNA Refseq : | NM_139286 |
Protein Refseq : | NP_644815 |
UniProt ID : | Q8NHZ8 |
Chromosome Location : | 9q32 |
Pathway : | APC/C complex;APC/C-mediated degradation of cell cycle proteins; APC/C: Cdc20 mediateddegradation of Cyclin B; APC/C: Cdc20 mediated degradation of Securin; APC/C:Cdc20 mediated degradation of mitotic proteins; APC/C: Cdh1 mediateddegradation of Cdc20 and other APC/C: Cdh1 targeted proteins in latemitosis/early G1; Activation of APC/C and APC/C: Cdc20 mediated degradationof mitotic proteins; Adaptive Immunity Signaling; Cell Cycle, Mitotic; Cellcycle; HTLV-I infection; Immune System; Inhibition of the proteolyticactivity of APC/C required for the onset of anaphase by mitotic spindlecheckpoint components; Oocyte meiosis; Phosphorylation of the APC/C;Regulation of APC/C activators between G1/S and early anaphase |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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