Recombinant Mouse Cdc26 Protein, Myc/DDK-tagged

• Cat.No.: Cdc26-2073M
• Product Overview: Purified recombinant protein of mouse full-length cell division cycle 26 (Cdc26), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.
• Molecular Mass: 10.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Cdc26 cell division cycle 26 [ Mus musculus (house mouse) ]
• Official Symbol: Cdc26
• Synonyms: CDC26; cell division cycle 26; anaphase-promoting complex subunit CDC26; cell division cycle protein 26 homolog; CDC26 subunit of anaphase promoting complex; 2010012C09Rik; MGC130281
• Gene ID: 66440
• mRNA Refseq: NM_139291
• Protein Refseq: NP_647452
• UniProt ID: Q99JP4