Recombinant Human Colony Stimulating Factor 1 (macrophage)
Cat.No. : | CSF1-339H |
Product Overview : | Recombinant human CSF1was expressed in E. coli and purified recombinant Human CSF1 protein. |
- Specification
- Gene Information
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Cat. No. : | CSF1-339H |
Description : | CSF1 is a potenthematopoietic factor produced by a variety of cells including lymphocytes,monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts. It is akey regulator of cellular proliferation, differentiation, and survival ofblood monocytes, tissue macrophages and their progenitor cells. CSF1 has beenshown to play important roles in modulating dermal thickness, and male andfemale fertility. CSF1 is clinically used in the treatment of infection,malignancies and atherosclerosis. It facilitates hematopoietic recovery afterbone marrow transplantation. |
Source : | Human |
Host : | E. coli |
Form : | Supplied as alyophilized powder. |
Purity : | > 98% pure by SDSPAGE and HPLC |
Sequence : | Region of M-CSFprotein corresponding to amino acids MEVSEHCSHM IGNGHLQILQ QLIDSQMETACLIEYKFVDQ EQLDDPVCYL KKAFVLVQVI IEETMRFKDN TPNANATERL QELSMKLNSC FIKDYKEQNEACVQTYKESP LRLLEKIKNF FNETKNFLEK DWNIFSKNCN DSLAKCSSRD VVTKP. |
Molecular Mass : | 18.1 kDa |
Applications : | Numerousapplications are possible with this product and should be tested by the enduser under their own laboratory conditions. |
Storage : | Store at 4 deg Cuntil reconstitution. Following reconstitution aliquot and freeze at -20 degC for long term storage. Avoid repeated freeze/thaw cycles. |
OfficialSymbol : | CSF1 |
Gene Name : | CSF1 colony stimulating factor 1(macrophage) [ Homo sapiens ] |
Synonyms : | CSF1; colony stimulating factor1 (macrophage); MCSF; MGC31930; colony stimulating factor 1;OTTHUMP00000013363; OTTHUMP00000013364; macrophage colony stimulating factor;M-CSF; CSF-1; Lanimostim; OTTHUMP00000013362 |
Gene ID : | 1435 |
mRNA Refseq : | NM_000757 |
Protein Refseq : | NP_000748 |
MIM : | 120420 |
UniProt ID : | P09603 |
Chromosome Location : | 1p21-p13 |
Pathway : | Cytokine-cytokine receptorinteraction; Hematopoietic cell lineage; Osteoclastdifferentiation; Rheumatoid arthritis; Signaling events mediated by PTP1B;Signaling events mediated by TCPTP |
Function : | cytokine activity; growthfactor activity; macrophage colony stimulating factor receptor binding;protein binding; protein homodimerization activity |
Products Types
◆ Recombinant Protein | ||
Csf1-2161R | Recombinant Rat Csf1 Protein, His&GST-tagged | +Inquiry |
CSF1-45H | Recombinant Active Human CSF1 Protein, His-tagged(C-ter) | +Inquiry |
CSF1-5383H | Recombinant Human Colony Stimulating Factor 1 (macrophage) | +Inquiry |
CSF1-2158H | Recombinant Human CSF1 Protein, His-tagged | +Inquiry |
CSF1-339C | Active Recombinant Cynomolgus/Rhesus CSF1 protein(Met1-Asn190), His-tagged | +Inquiry |
◆ Lysates | ||
CSF1-001MCL | Recombinant Mouse CSF1 cell lysate | +Inquiry |
CSF1-1934HCL | Recombinant Human CSF1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionCSF1 is implicated in tumor-associated macrophages, influencing tumor growth, invasion, and the tumor microenvironment.
Side effects may include immune-related adverse events, inflammation, and alterations in white blood cell counts.
Yes, there is ongoing research on combining CSF1-targeted therapies with other immunotherapies or conventional treatments to enhance efficacy.
Challenges include maintaining the balance of immune responses, potential off-target effects, and variability in patient responses.
Studies are exploring its role in neuroinflammation, neuroprotection, and potential therapeutic interventions for conditions like Alzheimer's disease.
Customer Reviews (3)
Write a reviewThe CSF1 protein is renowned for its exceptional quality and reliability, making it an ideal choice to fulfill my experimental requirements.
With its high purity and stability, this protein ensures dependable and accurate results, which are crucial for the success of my research endeavors.
Whether it is for investigating cellular pathways, studying protein functions, or exploring signaling cascades, the CSF1 protein offers unparalleled versatility and performance.
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