Native Human Coagulation Factor V (proaccelerin, labile factor)

• Cat.No.: F5-5300H
• Product Overview: Native Human F5 wasexpessed in human plasma. Its molecular weight is 330000 Dalton.

Specification

• Description: F5(pronounced factor five) is a protein of the coagulation system, rarelyreferred to as proaccelerin or labile factor. In contrast to most othercoagulation factors, it is not enzymatically active but functions as acofactor. Deficiency leads to predisposition for hemorrhage, while somemutations (most notably factor V Leiden) predispose for thrombosis.
• Source: Human plasma
• Species: Human
• Form: Liquid in 50%glycerol (v/v)
• Molecular Mass: 330 kDa
• Storage: Store in workingaliquots at -20°C . Avoid repeated freeze-thaw cycles.
• Concentration: 5.0 mg/ml

Gene Information

• Gene Name: F5 coagulation factor V (proaccelerin, labile factor) [ Homo sapiens ]
• Official Symbol: F5
• Synonyms: F5; coagulation factor V (proaccelerin, labile factor); coagulation factor V; factor V Leiden; proaccelerin, labile factor; activated protein c cofactor; coagulation factor V jinjiang A2 domain; FVL; PCCF; THPH2
• Gene ID: 2153
• mRNA Refseq: NM_000130
• Protein Refseq: NP_000121
• MIM: 612309
• UniProt ID: P12259
• Chromosome Location: 1q23
• Pathway: Blood Clotting Cascade, organism-specific biosystem; Common Pathway, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Formation of Fibrin Clot (Clotting Cascade), organism-specific biosystem; Hemostasis, organism-specific biosystem
• Function: copper ion binding; metal ion binding; protein binding