Native Human Ceruloplasmin (ferroxidase)

• Cat.No.: CP-5326H
• Product Overview: Native human CP was expressedin Human Plasma.

Specification

• Cat. No.: CP-5326H
• Description: Human CP is alsoknown as ferroxidase or iron(II):oxygen oxidoreductase. CP is an enzymesynthesized in the liver containing 8 atoms of copper in its structure.Although CP is often considered a copper transport protein, this is not itsprimary function, just as human hemoglobin is not a carrier of iron, althoughit contains iron. The main carrier for copper in the plasma of humans isalbumin. CP enzyme (ferroxidase) catalyzes the oxidation of ferrous iron (Fe2+)to ferric iron (Fe3+), therefore assisting in CP enzyme transportin the plasma in association with transferrin, which can only carry iron inthe ferric state.
• Form: Lyophilized
• Source: Human Plasma
• Purity: >96% by SDS PAGE
• Molecular Weight: 134 kDa
• Storage: Store at -20°C.
• Pathways: HIF-1-alpha transcription factor network; Ironuptake and transport; Metal ion SLC transporters; Porphyrin and chlorophyllmetabolism; SLC-mediated transmembrane transport; Transmembrane transport ofsmall molecules; Transport of glucose and other sugars

Gene Information

• Gene Name: CP ceruloplasmin (ferroxidase) [Homo sapiens ]
• Official Symbol: CP
• Synonyms: CP; ceruloplasmin(ferroxidase); CP-2; ceruloplasmin; Ceruloplasmin; Ferroxidase; OTTHUMP00000197026;OTTHUMP00000215840; OTTHUMP00000215841; EC1.16.3.1
• Gene ID: 1356
• mRNA Refseq: NM_000096
• Protein Refseq: NP_000087
• MIM: 117700
• UniProt ID: P00450
• Chromosome Location: 3q23-q25
• Function: chaperonebinding; copper ion binding; ferroxidase activity; metal ion binding; oxidoreductaseactivity