Native Human Butyrylcholinesterase

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Native Human Butyrylcholinesterase

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Cat. No. : BCHE-5291H
Product Overview : Native human BCHEexpressed in Human Serum is a major acetylcholine hydrolyzing enzyme found inthe blood circulation.
Description : Butyrylcholinesterase (also knownas pseudocholinesterase, plasma cholinesterase, BCHE, or BuChE) is anon-specific cholinesterase enzyme that hydrolyses many different cholineesters. In humans, it is found primarily in the liver and is encoded by the BCHEgene. Butyrylcholine is a synthetic compound and does not occur in the bodynaturally. It is used as a tool to distinguish between acetyl- and BCHE.
Form : Lyophilized from0.02 M NH4HCO3 Buffer.
Source : Human Serum
Biological Activity : > 100 U/mgprotein. One unit will hydrolyze 1.0 µmole of butyrylcholine to choline andbutyrate per minute at pH 8.0 at 37°C.
Storage : Store at -20°C.Stable for 1 year. Avoid repeated freeze-thaw cycles.
Pathways : Diabetes pathways; Irinotecan Pathway;Synthesis
PDBrendering based on 1p0i. :

Gene Name : BCHE butyrylcholinesterase [ Homosapiens ]
Official Symbol : BCHE
Synonyms : BCHE;butyrylcholinesterase; E1; CHE1; cholinesterase; cholinesterase 1;OTTHUMP00000212636; choline esterase II; pseudocholinesterase; butyrylcholineesterase; acylcholine acylhydrolase
Gene ID : 590
mRNA Refseq : NM_000055
Protein Refseq : NP_000046
MIM : 177400
UniProt ID : P06276
Chromosome Location : 3q26.1-q26.2
Function : acetylcholinesteraseactivity; beta-amyloid binding; carboxylesterase activity; catalyticactivity; choline binding; cholinesterase activity; enzyme binding; hydrolaseactivity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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