Recombinant Human Adrenergic, Beta, Receptor Kinase 1, His-tagged
Cat.No. : | ADRBK1-357H |
Product Overview : | Recombinant humanADRBK1 with His Tag is a serine/threonine kinase. |
- Specification
- Gene Information
- Related Products
Cat. No. : | ADRBK1-357H |
Description : | Many of the Gprotein-coupled receptors are known tobe phosphorylated by G protein-dependent receptor kinases (GRKs). ADRBK1 (also referred to as βARK or BARK) is aserine/threonine intracellular kinase. It is activated by PKA and its targetis the beta adrenergic receptor. It is one method by which the cell willdesensitize itself from epinephrine overstimulation. |
Source : | Insect cells |
Species : | Human |
Form : | Liquid in 50 mMTris-HCl, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02%. Triton X-100 + 2 mM DTT+ 50% glycerol. |
Molecular Weight : | 82.3 kDa |
Concentration : | 0.5 mg/ml |
Purity : | > 95% asdetermined by SDS-PAGE analysis. |
Storage : | Stable for 6 monthsin working aliquots at -80°C. Avoid repeated freeze-thaw cycles. |
OfficialSymbol : | ADRBK1 |
Gene Name : | ADRBK1 adrenergic, beta, receptorkinase 1 [ Homo sapiens ] |
Synonyms : | ADRBK1; adrenergic,beta, receptor kinase 1; GRK2; BARK1; FLJ16718; BETA-ARK1; beta-adrenergicreceptor kinase 1; beta-ARK-1; OTTHUMP00000235171; G-protein coupled receptorkinase 2; EC 2.7.11.15; BETA-ARK1; EC 2.7.11 |
Gene ID : | 156 |
mRNA Refseq : | NM_001619 |
Protein Refseq : | NP_001610 |
MIM : | 109635 |
UniProt ID : | P25098 |
Chromosome Location : | 11q13.1 |
Pathway : | CXCR4-mediatedsignaling events; Ca-dependent events; CaM pathway; Calmodulin inducedevents; Chemokine signaling pathway; DAG and IP3 signaling; Downstream signaltransduction; EGFR interacts with phospholipase C-gamma; Endocytosis; GPCRdownstream signaling; NGF signalling via TRKA from the plasma membrane;Opioid Signalling; PLC beta mediated events; Phospholipase C-mediatedcascade; Signaling by EGFR; Signalling by NGF; Thromboxane A2 receptorsignaling |
Function : | ATP binding; Edg-2lysophosphatidic acid receptor binding; G-protein coupled receptor kinaseactivity; alpha-2A adrenergic receptor binding; beta-adrenergic receptorkinase activity; nucleotide binding; protein binding; protein kinaseactivity; signal transducer activity |
Products Types
◆ Recombinant Protein | ||
ADRBK1-978H | Recombinant Human ADRBK1 protein(Met1-Leu689), His&GST-tagged | +Inquiry |
ADRBK1-202R | Recombinant Rat ADRBK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ADRBK1-2437H | Recombinant Human ADRBK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ADRBK1-152H | Recombinant Human ADRBK1 | +Inquiry |
ADRBK1-3006C | Recombinant Chicken ADRBK1 | +Inquiry |
◆ Lysates | ||
ADRBK1-625HCL | Recombinant Human ADRBK1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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