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Native Human Amylase, Alpha 2B (pancreatic)

Cat. No.: AMY2B-1858H
Product Overview: Native human AMY2B wasexpressed in Human Pancreas.
Description: Amylases aresecreted proteins that hydrolyze 1,4-alpha-glucoside bonds inoligosaccharides and polysaccharides, and thus catalyze the first step indigestion of dietary starch and glycogen. The human genome has a cluster ofseveral amylase genes that are expressed at high levels in either salivarygland or pancreas. This gene encodes an amylase isoenzyme produced by thepancreas.
Form: Aqueous buffer of100 mM Tris-HCL+150 mM NaCl.
Source: Human Pancreas
Biological Activity: Typically > 400Units/ml at 37 oC. One unit will catalyze thehydrolysis of one of malto pentaose, which through coupled reactions resultsin the formation of 5 of glucose-6-phosphate per minute at 37 oC.Measured at 340 nm as an equimolar amount of NADH produced by a coupledreaction.
Purity: > 95.0% asdetermined by RP-HPLC and SDS-PAGE analyses.
Storage: Liquid is stable for1 year at 2-4oC. Avoid repeated freeze-thaw cycles.
Pathways: Carbohydrate digestion and absorption; Digestionof dietary carbohydrate; Metabolic pathways; Metabolism of carbohydrates; Pancreaticsecretion; Starch and sucrose metabolism
Gene Name: AMY2B amylase, alpha 2B(pancreatic) [ Homo sapiens ]
Official Symbol: AMY2B
Synonyms: AMY2B; amylase,alpha 2B (pancreatic); AMY2; alpha-amylase 2B;glycogenase; OTTHUMP00000012696; OTTHUMP00000012697; alpha-amylase carcinoid;carcinoid alpha-amylase; 1,4-alpha-D-glucan glucanohydrolase 2B; EC 3.2.1.1
Gene ID: 280
mRNA Refseq: NM_020978
Protein Refseq: NP_066188
MIM: 104660
UniProt ID: P19961
Chromosome Location: 1
Function: alpha-amylaseactivity; hydrolase activity, acting on glycosyl bonds; metal ion binding

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