Native Rat Coagulation Factor II

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Native Rat Coagulation Factor II

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Cat. No. : F2-5286R
Product Overview : Rat F2 isprepared from fresh frozen rat plasma. Purity is determined by SDS PAGE analysis.
Description : F2is proteolytically cleaved to form thrombin in the first step of thecoagulation cascade, which ultimately results in the stemming of blood loss.F2 in turn acts as a serine protease that converts soluble fibrinogen intoinsoluble strands of fibrin, as well as catalyzing many othercoagulation-related reactions.
Source : Rat plasma
Form : Liquid in 50%Glycero.
Purity : > 95% by SDS-PAGEanalysis.
MolecularWeight : 72,000
Concentration : 5.0mg/ml
Storage : Store at -20°C.
Pathways : BloodClotting Cascade; Cell surface interactions at the vascular wall; ClassA/1(Rhodopsin-like receptors); Common Pathway; Complement and CoaqulationCascades; Diabetes pathways; FOXA2 and FOXA3 transcription factor networks; ExtrinsicPathway; Formation of Fibrin Clot (Clotting Cascade); Hemostasis; IntrinsicPathway; Regulation of actin cytoskeleton; Selenium Pathway; SignalTransduction
Gene Name : F2coagulation factor II [ Rattus norvegicus]
Official Symbol : F2
Synonyms : F2; coagulation factor II; prothrombin; thrombin; coagulationfactor2; EC 3.4.21.5
Gene ID : 29251
mRNA Refseq : NM_022924
Protein Refseq : NP_075213
Chromosome Location : 3q24
Function : peptidase activity; serine-typeendopeptidase activity; calcium ion binding; receptor binding; contributes toreceptor binging; thrombospondin receptor activity

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