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Native Human, Coagulation factor X

Cat.No.: F10-355H
Product Overview: Native human F10 was expressed in Human Plasma.
Description: F10 isactivated into factor Xa by both factor IX (with its cofactor, factor VIII ina complex known as intrinsic Xase) and factor VII with its cofactor, tissuefactor (a complex known as extrinsic Xase). It is therefore the first memberof the final common pathway or thrombin pathway. It acts by cleavingprothrombin in two places, which yields the active thrombin. This process isoptimized when factor Xa is complexed with activated co-factor V in theprothrombinase complex.
Source: Human plasma
Species: Human
Form: Liquid in 50% (v/v)glycerol/H20.
Molecular Mass: 46 kDa
Storage: Store in workingaliquots at -20°C . Avoid repeated freeze-thaw cycles.
Concentration: 5.0 mg/ml
Gene Name: F10 coagulation factor X [ Homo sapiens ]
Official Symbol: F10
Synonyms: F10; coagulation factor X; factor Xa; prothrombinase; Stuart-Prower factor; FX; FXA;
Gene ID: 2159
mRNA Refseq: NM_000504
Protein Refseq: NP_000495
MIM: 613872
UniProt ID: P00742
Chromosome Location: 13q34
Pathway: Blood Clotting Cascade, organism-specific biosystem; Common Pathway, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Extrinsic Pathway, organism-specific biosystem; Formation of Fibrin Clot (Clotting Cascade), organism-specific biosystem;
Function: calcium ion binding; peptidase activity; phospholipid binding; protein binding; serine-type endopeptidase activity; serine-type endopeptidase activity;

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