Recombinant Human Cyclin E2, T7-tagged

• Cat.No.: CCNE2-2918H
• Product Overview: Recombinant Human CCNE2 protein was expressed in E.coliwith T7-tag at the N-terminus. The molecular weight is 46757 Da(296 aa).

Specification

• Cat. No.: CCNE2-2918H
• Description: Cyclin E2 is a member of the cyclin family. Cyclin E2 binds to G1 phase Cdk2, which is required for the transition from G1 to S phase. The Cyclin E/CDK2 complex phosphorylates p27Kip1 (an inhibitor of Cyclin D), tagging it for degradation, thus promoting expression of Cyclin A, allowing progression to S phase.
• Sequences of amino acids: 1-296 aa
• Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3.
• Purity: 95%

Gene Information

• Gene Name: CCNE2 cyclin E2 [ Homo sapiens ]
• Synonyms: CYCE2; CCNE2; G1/S-specific cyclin-E2G1/S-specific cyclin E2
• Gene ID: 9134
• mRNA Refseq: NM_057749
• Protein Refseq: NP_477097
• MIM: 603775
• UniProt ID: O96020
• Chromosome Location: 8q22.1
• Pathway: Cell cycle; Oocyte meiosis; Pathways in cancer; Prostate cancer; Small cell lung cancer; p53 signaling pathway; Cell Cycle Checkpoints; Cell Cycle; Mitotic
• Function: cyclin-dependent protein kinase regulator activity; protein binding