"CCNE2" Related Products

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Recombinant Human Cyclin E2, T7-tagged

Cat. No.: CCNE2-2918H
Product Overview: Recombinant Human CCNE2 protein was expressed in E.coliwith T7-tag at the N-terminus. The molecular weight is 46757 Da(296 aa).
Description: Cyclin E2 is a member of the cyclin family. Cyclin E2 binds to G1 phase Cdk2, which is required for the transition from G1 to S phase. The Cyclin E/CDK2 complex phosphorylates p27Kip1 (an inhibitor of Cyclin D), tagging it for degradation, thus promoting expression of Cyclin A, allowing progression to S phase.
Sequences of amino acids: 1-296 aa
Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3.
Purity: 95%
Gene Name: CCNE2 cyclin E2 [ Homo sapiens ]
Synonyms: CYCE2; CCNE2; G1/S-specific cyclin-E2G1/S-specific cyclin E2
Gene ID: 9134
mRNA Refseq: NM_057749
Protein Refseq: NP_477097
MIM: 603775
UniProt ID: O96020
Chromosome Location: 8q22.1
Pathway: Cell cycle; Oocyte meiosis; Pathways in cancer; Prostate cancer; Small cell lung cancer; p53 signaling pathway; Cell Cycle Checkpoints; Cell Cycle; Mitotic
Function: cyclin-dependent protein kinase regulator activity; protein binding

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