"CCNE2" Related Products

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Recombinant Human Cyclin E2, T7-tagged

Cat. No. : CCNE2-2918H
Product Overview : Recombinant Human CCNE2 protein was expressed in E.coliwith T7-tag at the N-terminus. The molecular weight is 46757 Da(296 aa).
Description : Cyclin E2 is a member of the cyclin family. Cyclin E2 binds to G1 phase Cdk2, which is required for the transition from G1 to S phase. The Cyclin E/CDK2 complex phosphorylates p27Kip1 (an inhibitor of Cyclin D), tagging it for degradation, thus promoting expression of Cyclin A, allowing progression to S phase.
Sequences of amino acids : 1-296 aa
Formulation : 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3.
Purity : 95%
Gene Name : CCNE2 cyclin E2 [ Homo sapiens ]
Synonyms : CYCE2; CCNE2; G1/S-specific cyclin-E2G1/S-specific cyclin E2
Gene ID : 9134
mRNA Refseq : NM_057749
Protein Refseq : NP_477097
MIM : 603775
UniProt ID : O96020
Chromosome Location : 8q22.1
Pathway : Cell cycle; Oocyte meiosis; Pathways in cancer; Prostate cancer; Small cell lung cancer; p53 signaling pathway; Cell Cycle Checkpoints; Cell Cycle; Mitotic
Function : cyclin-dependent protein kinase regulator activity; protein binding

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