Recombinant Human Charged Multivesicular Body Protein 4A, His-tagged CHMP4A-1376H

Recombinant Human Charged Multivesicular Body Protein 4A, His-tagged

PRODUCTS

Home / Products / Recombinant Proteins / Recombinant Human Charged Multivesicular Body Protein 4A, His-tagged

Recombinant Human Charged Multivesicular Body Protein 4A, His-tagged

CHMP4A Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat. No. : CHMP4A-1376H
Product Overview : Recombinant humanCHMP4A protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography techniques.
Description : CHMP4A(Chromatin-modifying protein 4a) belongs to the SNF7 family and functions aschromatin-modifying proteins. It probable core component of the endosomalsorting required for transport complex III (ESCRT-III) which is involved inmultivesicular bodies (MVBs) formation and sorting of endosomal cargoproteins into MVBs. Also during HIV-1 infection, the virus uses the ESCRT-IIIcomplex to mediate budding and exocytosis of viral proteins via theassociation of CHMP4 and a protein recruited by HIV-1 p6, which is present inviral Gag assembly and budding. CHMP4A expressed at higher level in heart,kidney, liver and skeletal muscle.
Form : Liquid. In 20mMTris-HCl buffer (pH 8.0) containing 2mM DTT, 50% glycerol, 200mM NaCl, 0.1mMPMSF, 1mM EDTA.
Molecular Weight : 32.0 kDa (285aa),confirmed by MALDI-TOF.
Purity : > 90% by SDS-PAGE
Concentration : 0.25 mg/ml(determined by Bradford assay)
Sequences of aminoacids : MGSSHHHHHHSSGLVPRGSH MSRRRPEDGL GKAGPCVMRH HPPRSKAEVW RTLRGGGGRG ELAMSGLGRLFGKGKKEKGP TPEEAIQKLK ETEKILIKKQ EFLEQKIQQE LQTAKKYGTK NKRAALQALR RKKRFEQQLAQTDGTLSTLE FQREAIENAT TNAEVLRTME LAAQSMKKAY QDMDIDKVDE LMTDITEQQE VAQQISDAISRPMGFGDDVD EDELLEELEE LEQEELAQEL LNVGDKEEEP SVKLPSVPST HLPAGPAPKV DEDEEALKQLAEWVS
Storage : Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways : ESCRT-III complex;Endocytosis; Endosomal Sorting Complex Required For Transport (ESCRT);Membrane Trafficking
Gene Name : CHMP4A charged multivesicularbody protein 4A [ Homo sapiens ]
Official Symbol : CHMP4A
Synonyms : CHMP4A; charged multivesicular body protein 4A; SNF7;CHMP4; SHAX2; CHMP4B; SNF7-1; VPS32A; HSPC134; VPS32-1; FLJ61658; C14orf123;MGC142093; MGC142095; charged multivesicular body protein 4a;OTTHUMP00000164694; OTTHUMP00000235236; chromatin modifying protein 4A; SNF7homolog associated with Alix-2; Snf7 homologue associated with Alix 2;vacuolar protein sorting-associated protein 32-1
Gene ID : 29082
mRNA Refseq : NM_014169
Protein Refseq : NP_054888
MIM : 610051
UniProt ID : Q9BY43
Chromosome Location : 14q11.2
Function : lipid binding

Online Inquiry


  • Note: There will be extra charge for optional service!
  • Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2007 – 2020 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy