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Recombinant Human Prion Protein, His-tagged

Cat. No.: PRNP-1898H
Product Overview: Recombinant humanfull length native cellular form of PRNP contains amino acids 23-231 andN-terminal His tag.
Description: The PRNP conformation of the protein afterrefolding procedure was confirmed by high resolution NMR spectroscopy.
Source: E. coli
Species: Human
Form: Liquid in 10 mMsodium acetate, pH 4.5 + 0.02% sodium azide. Precaution: Sodium azide is apoisonous and hazardous substance which should be handled by trained staffonly.
Purity: > 95% asdetermined by SDS-PAGE analysis
Storage: Stable for 1 year inworking aliquots at -80°C. Avoid repeated freeze-thaw cycles.
OfficialSymbol: PRNP
Gene Name: PRNP prion protein [ Homosapiens ]
Synonyms: PRNP; prion protein;CJD;GSS; PrP; ASCR; PRIP; PrPc; CD230; prion; PrP27-30; PrP33-35C; major prionprotein; p27-30; CD230 antigen; prion protein PrP; OTTHUMP00000030161; OTTHUMP00000030162;OTTHUMP00000030163; OTTHUMP00000161139; prion-related protein; prion protein(p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome,fatal familial insomnia)
Gene ID: 5621
mRNA Refseq: NM_000311
Protein Refseq: NP_000302
MIM: 176640
UniProt ID: O75942
Chromosome Location: 20p13
Pathway: Axon guidance; Developmental Biology;Glypican 1 network; NCAM signaling for neurite out-growth; NCAM1interactions; Prion diseases
Function: ATP-dependent protein binding; chaperonebinding; copper ion binding; identical protein binding; metal ion binding;microtubule binding; protein binding; tubulin binding

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