Recombinant Human Prion Protein, His-tagged

• Cat.No.: PRNP-1898H
• Product Overview: Recombinant humanfull length native cellular form of PRNP contains amino acids 23-231 andN-terminal His tag.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 23-231 a.a.
• Description: The PRNP conformation of the protein afterrefolding procedure was confirmed by high resolution NMR spectroscopy.
• Form: Liquid in 10 mMsodium acetate, pH 4.5 + 0.02% sodium azide. Precaution: Sodium azide is apoisonous and hazardous substance which should be handled by trained staffonly.
• Purity: > 95% asdetermined by SDS-PAGE analysis
• Storage: Stable for 1 year inworking aliquots at -80°C. Avoid repeated freeze-thaw cycles.
• OfficialSymbol: PRNP
• Full Length: Full L.

Gene Information

• Gene Name: PRNP prion protein [ Homosapiens ]
• Synonyms: PRNP; prion protein;CJD;GSS; PrP; ASCR; PRIP; PrPc; CD230; prion; PrP27-30; PrP33-35C; major prionprotein; p27-30; CD230 antigen; prion protein PrP; OTTHUMP00000030161; OTTHUMP00000030162;OTTHUMP00000030163; OTTHUMP00000161139; prion-related protein; prion protein(p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome,fatal familial insomnia)
• Gene ID: 5621
• mRNA Refseq: NM_000311
• Protein Refseq: NP_000302
• MIM: 176640
• UniProt ID: O75942
• Chromosome Location: 20p13
• Pathway: Axon guidance; Developmental Biology;Glypican 1 network; NCAM signaling for neurite out-growth; NCAM1interactions; Prion diseases
• Function: ATP-dependent protein binding; chaperonebinding; copper ion binding; identical protein binding; metal ion binding;microtubule binding; protein binding; tubulin binding