Species : |
Hamster |
Source : |
E.coli |
Tag : |
Non |
Protein Length : |
23-231 aa |
Description : |
Prion Protein (PrP) is an abundant cellular protein in mammalian neural tissue. It is associated with mammalian prion diseases, e.g. transmissible spongiforme encephalophathies that include human Creutzfeld-Jakob disease, bovine spongiforme encephalopathy, sheep scrapie, cervid’s chronic wasting disease and various rodent prion diseases. In the disease process, PrP undergoes protein aggregation into disease specific PrPSc. |
Form : |
Finally dialysed in pure water, shock frozen in liquid nitrogen at a protein concentration of 0.25 mg/ml |
Molecular Mass : |
23117 kg/mol |
AA Sequence : |
GSKKRPKPGGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGGWGQGGTHGQWNKPSKPKTNMKHVAGAAAAGAVVGGLGGYMLGSAMSRP LIHFGSDYEDRYYRENMHRYPNQVYYRPVDQYSNQNNFVHDCVNITVKEHTVTTTTKGENFTETDIKMMERVVEQMCITQYQRESQAYYQRGA |
Purity : |
> 95% by SDS-PAGE |
Applications : |
Prion Protein is frequently used in analytical aggregation assays |
Notes : |
Thawing: Gentle agitation at 37 centigrade until no ice is left. Keep on ice. Do not refreeze |
Storage : |
Store at -80 centigrade |
Concentration : |
0.25 mg/ml |