Recombinant Human PTK6 Protein Tyrosine Kinase 6, His-tagged
Cat.No. : | PTK6-1905H |
Product Overview : | Recombinant humanfull length PTK6 with His Tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PTK6-1905H |
Description : | PTK6, also known as Breasttumor Kinase (BRK), is a Src-like nonreceptor tyrosine kinase, which belongsto Tyr protein kinase family. It is overexpressed in the majority of breastcancer and several other cancer types, while being detected at appreciablelevels in only a limited range of adult tissues that does not include themammary gland. PTK6 contains SH3, SH2, and Kinase domains, with a linkerregion (Linker) between the SH2 and Kinase domains, and the structural basisof the SH3-Linker interaction that results in auto-inhibition of PTK6. |
Source : | insect cells |
Species : | Human |
Form : | Liquid in 50 mMTris, pH 7.5 + 200 mM NaCl + 1 mM EDTA + 0.05% Triton X-100 + 5 mM DTT + 50%glycerol. |
Molecular Weight : | 55.4 kDa |
Purity : | ≥ 95% |
Biological Activity : | 166 nmole ofphosphate transferred to poly [Glu,Tyr] 4:1 substrate per minute per mg oftotal protein at 30°C. Activity determined at a final protein concentrationof 2 ug/ml. |
Storage : | Stablefor 6 months in working aliquots at -80°C. Avoid repeated freeze-thaw cycles. |
OfficialSymbol : | PTK6 |
Gene Name : | PTK6 PTK6 protein tyrosinekinase 6 [ Homo sapiens ] |
Synonyms : | PTK6; PTK6 protein tyrosinekinase 6; BRK; FLJ42088; breast tumor kinase; protein-tyrosine kinase BRK; EC2.7.10.2; Tyrosine-protein kinase 6; OTTHUMP00000031656; Tyrosine-proteinkinase BRK |
Gene ID : | 5753 |
mRNA Refseq : | NM_005975 |
Protein Refseq : | NP_005966 |
MIM : | 602004 |
UniProt ID : | Q13882 |
Chromosome Location : | 20q13.3 |
Pathway : | EGFR1 Signaling Pathway; Focal Adhesion |
Function : | ATP binding; non-membranespanning protein tyrosine kinase activity; nucleotide binding; proteinbinding; protein serine/threonine kinase activity; transferase activity |
Products Types
◆ Recombinant Protein | ||
PTK6-1798H | Recombinant Human PTK6 Protein, His (Fc)-Avi-tagged | +Inquiry |
PTK6-0759H | Recombinant Human PTK6 Protein (V2-T451), Tag Free | +Inquiry |
Ptk6-5228M | Recombinant Mouse Ptk6 Protein, Myc/DDK-tagged | +Inquiry |
PTK6-3109H | Recombinant Human PTK6 Protein, MYC/DDK-tagged | +Inquiry |
PTK6-0760H | Recombinant Human PTK6 Protein (V2-T451), His/GST tagged | +Inquiry |
◆ Lysates | ||
PTK6-001MCL | Recombinant Mouse PTK6 cell lysate | +Inquiry |
PTK6-709HCL | Recombinant Human PTK6 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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