Natve Human Thrombospondin

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Natve Human Thrombospondin

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Cat.No. : THBS1-5524H
Product Overview : Natve Human Thrombospondin was purified from Human plasma.
Description : The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis.
Source : Human plasma
Species : Human
Form : Lyophilized powder
Molecular Mass : 420000
Purity : ≥95% by SDS-PAGE analysis
Storage : -70 C
Storage Buffer : 0.02M Tris-HCl; 0.6M NaCl; 0.001M CaCl2; 20% Sucrose; pH 7.8
Gene Name : THBS1 thrombospondin 1 [ Homo sapiens ]
Official Symbol : THBS1
Synonyms : THBS1; thrombospondin 1; thrombospondin-1; THBS; THBS 1; thrombospondin 1p180; TSP; TSP 1; TSP1; thrombospondin-1p180; TSP-1; THBS-1;
Gene ID : 7057
mRNA Refseq : NM_003246
Protein Refseq : NP_003237
MIM : 188060
UniProt ID : P07996
Chromosome Location : 15q15
Pathway : Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem;
Function : calcium ion binding; collagen V binding; eukaryotic cell surface binding; fibrinogen binding; fibroblast growth factor binding; fibronectin binding; glycoprotein binding; heparin binding; identical protein binding; integrin binding; laminin binding; low-density lipoprotein particle binding; phosphatidylserine binding; protein binding; proteoglycan binding; structural molecule activity; transforming growth factor beta binding; transforming growth factor beta binding;

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