Natve Human Thrombospondin

• Cat.No.: THBS1-5524H
• Product Overview: Natve Human Thrombospondin was purified from Human plasma.

Specification

• Description: The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis.
• Source: Human plasma
• Species: Human
• Form: Lyophilized powder
• Molecular Mass: 420000
• Purity: ≥95% by SDS-PAGE analysis
• Storage: -70 C
• Storage Buffer: 0.02M Tris-HCl; 0.6M NaCl; 0.001M CaCl2; 20% Sucrose; pH 7.8

Gene Information

• Gene Name: THBS1 thrombospondin 1 [ Homo sapiens ]
• Official Symbol: THBS1
• Synonyms: THBS1; thrombospondin 1; thrombospondin-1; THBS; THBS 1; thrombospondin 1p180; TSP; TSP 1; TSP1; thrombospondin-1p180; TSP-1; THBS-1
• Gene ID: 7057
• mRNA Refseq: NM_003246
• Protein Refseq: NP_003237
• MIM: 188060
• UniProt ID: P07996
• Chromosome Location: 15q15
• Pathway: Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem
• Function: calcium ion binding; collagen V binding; eukaryotic cell surface binding; fibrinogen binding; fibroblast growth factor binding; fibronectin binding; glycoprotein binding; heparin binding; identical protein binding; integrin binding; laminin binding; low-density lipoprotein particle binding; phosphatidylserine binding; protein binding; proteoglycan binding; structural molecule activity; transforming growth factor beta binding; transforming growth factor beta binding