Recombinant Human S100 Calcium Binding Protein A11, His-tagged
Cat.No. : | S100A11-5480H |
Product Overview : | Recombinant HumanS100A11 is expressed in E. coli having a molecular weight of 17kDa fused toan amino terminal hexahistidine tag. |
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- Gene Information
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Cat. No. : | S100A11-5480H |
Description : | Protein S100A11 is a protein that in humans is encoded bythe S100A11 gene. The protein encoded by this gene is a member of the S100A11family of proteins containing 2 EF-hand calcium-binding motifs. S100A11proteins are localized in the cytoplasm and/or nucleus of a wide range ofcells, and involved in the regulation of a number of cellular processes suchas cell cycle progression and differentiation. |
Source : | E. coli |
Species : | Human |
Form : | The protein isconcentrated in a liquid (1.96 mg/ml) containing in PBS/50% glycerol. |
Purity : | Greater than95%(SDS-PAGE).2 bands on Western blot at 17 and 34 kDa,respectively representingmonomeric and dimeric form. |
Molecular Weight : | 17 kDa |
Storage : | Store at 2-4°C ifentire vial will be used within 1-2 weeks. Store, frozen at -20°C forlonger periods oftime. Please avoid freeze-thaw cycles. |
OfficialSymbol : | S100A11 |
Gene Name : | S100A11 S100 calcium bindingprotein A11 [ Homo sapiens ] |
Synonyms : | S100A11;S100 calcium binding protein A11; MLN70; S100C; proteinS100-A11; calgizzarin; protein S100-C; metastatic lymph node gene 70 protein;S100 calcium-binding protein A11 (calgizzarin); ProteinS100-A11; Calgizzarin; Metastatic lymph nodegene 70 protein; Protein S100-C; OTTHUMP00000015271 |
Gene ID : | 6282 |
mRNA Refseq : | NM_005620 |
Protein Refseq : | NP_005611 |
MIM : | 603114 |
UniProt ID : | P31949 |
Chromosome Location : | 1q21 |
Function : | S100 beta binding; calciumion binding; calcium-dependent protein binding; protein binding; proteinhomodimerization activity |
Products Types
◆ Recombinant Protein | ||
S100A11-1935H | Recombinant Human S100A11 Protein, His (Fc)-Avi-tagged | +Inquiry |
S100a11-5665M | Recombinant Mouse S100a11 Protein, Myc/DDK-tagged | +Inquiry |
S100A11-4870R | Recombinant Rat S100A11 Protein, His (Fc)-Avi-tagged | +Inquiry |
S100A11-7865M | Recombinant Mouse S100A11 Protein, His (Fc)-Avi-tagged | +Inquiry |
S100A11-307M | Recombinant Mouse S100A11 protein, His-tagged | +Inquiry |
◆ Native Protein | ||
S100A11-3111H | Native Human S100A11 protein(Met1-Thr105) | +Inquiry |
◆ Lysates | ||
S100A11-2095HCL | Recombinant Human S100A11 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionS100A11 participates in multiple signaling pathways, influencing cancer progression and metastasis. It interacts with proteins involved in cell motility, invasion, and angiogenesis, contributing to the malignant phenotype.
S100A11 plays a role in cellular differentiation, influencing specific target genes and pathways. Its involvement in differentiation programs is context-dependent and varies across cell types.
S100A11 expression is regulated at transcriptional and post-translational levels. Transcription factors and signaling pathways control its mRNA levels, while post-translational modifications such as phosphorylation modulate its activity.
Emerging evidence suggests a potential role for S100A11 in neurodegenerative diseases. The mechanisms linking S100A11 to neurological pathology involve its interactions with proteins and signaling cascades.
S100A11 is a member of the S100 protein family, predominantly located in the cytoplasm and nucleus. Its physiological roles include regulation of cell proliferation, differentiation, and apoptosis.
Customer Reviews (3)
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