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Recombinant Human S100 Calcium Binding Protein A11, His-tagged

Cat.No. : S100A11-5480H
Product Overview : Recombinant HumanS100A11 is expressed in E. coli having a molecular weight of 17kDa fused toan amino terminal hexahistidine tag.
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Cat. No. : S100A11-5480H
Description : Protein S100A11 is a protein that in humans is encoded bythe S100A11 gene. The protein encoded by this gene is a member of the S100A11family of proteins containing 2 EF-hand calcium-binding motifs. S100A11proteins are localized in the cytoplasm and/or nucleus of a wide range ofcells, and involved in the regulation of a number of cellular processes suchas cell cycle progression and differentiation.
Source : E. coli
Species : Human
Form : The protein isconcentrated in a liquid (1.96 mg/ml) containing in PBS/50% glycerol.
Purity : Greater than95%(SDS-PAGE).2 bands on Western blot at 17 and 34 kDa,respectively representingmonomeric and dimeric form.
Molecular Weight : 17 kDa
Storage : Store at 2-4°C ifentire vial will be used within 1-2 weeks. Store, frozen at -20°C forlonger periods oftime. Please avoid freeze-thaw cycles.
OfficialSymbol : S100A11
Gene Name : S100A11 S100 calcium bindingprotein A11 [ Homo sapiens ]
Synonyms : S100A11;S100 calcium binding protein A11; MLN70; S100C; proteinS100-A11; calgizzarin; protein S100-C; metastatic lymph node gene 70 protein;S100 calcium-binding protein A11 (calgizzarin); ProteinS100-A11; Calgizzarin; Metastatic lymph nodegene 70 protein; Protein S100-C; OTTHUMP00000015271
Gene ID : 6282
mRNA Refseq : NM_005620
Protein Refseq : NP_005611
MIM : 603114
UniProt ID : P31949
Chromosome Location : 1q21
Function : S100 beta binding; calciumion binding; calcium-dependent protein binding; protein binding; proteinhomodimerization activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can you elaborate on the role of S100A11 in cellular signaling pathways, particularly those involved in cancer progression and metastasis? 01/12/2021

S100A11 participates in multiple signaling pathways, influencing cancer progression and metastasis. It interacts with proteins involved in cell motility, invasion, and angiogenesis, contributing to the malignant phenotype.

How does S100A11 contribute to cellular differentiation, and are there specific target genes or pathways involved in this process? 05/23/2020

S100A11 plays a role in cellular differentiation, influencing specific target genes and pathways. Its involvement in differentiation programs is context-dependent and varies across cell types.

How is S100A11 expression regulated, and what are the transcriptional and post-translational mechanisms influencing its activity? 04/07/2019

S100A11 expression is regulated at transcriptional and post-translational levels. Transcription factors and signaling pathways control its mRNA levels, while post-translational modifications such as phosphorylation modulate its activity.

In neurodegenerative diseases, is there evidence of S100A11 involvement, and what are the potential mechanisms linking this protein to neurological pathology? 11/14/2018

Emerging evidence suggests a potential role for S100A11 in neurodegenerative diseases. The mechanisms linking S100A11 to neurological pathology involve its interactions with proteins and signaling cascades.

What is S100A11, and what is its cellular localization and physiological role? 08/29/2018

S100A11 is a member of the S100 protein family, predominantly located in the cytoplasm and nucleus. Its physiological roles include regulation of cell proliferation, differentiation, and apoptosis.

Customer Reviews (3)

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Reviews
03/09/2021

    Quality product, delivered on time—perfect!

    01/30/2019

      Fantastic quality, hassle-free delivery!

      10/16/2018

        A+ for both product quality and excellent service!

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