Recombinant Monkey Colony Stimulating Factor 2 (granulocyte-macrophage)
Cat.No. : | CSF2-382M |
Product Overview : | Recombinant MonkeyCSF2 is a single non-glycosylated polypeptide chain containing 127 aminoacids. |
- Specification
- Gene Information
- Related Products
Cat. No. : | CSF2-382M |
Description : | CSF2 was initiallycharacterized as a growth factor that can support the in vitro colonyformation of granulocyte-macrophage progenitors. It is produced by a numberof different cell types (including activated T cells, B cells, macrophages,mast cells, endothelial cells and fibroblasts) in response to cytokine orimmune and inflammatory stimuli. Besides granulocyte-macrophage progenitors,CSF2 is also a growth factor for erythroid, megakaryocyte and eosinophilprogenitors. On mature hematopoietic cells, CSF2 is a survival factor for andactivates the effector functions of granulocytes, monocytes, macrophages, andeosinophils. |
Source : | E. coli |
Species : | Monkey |
Form : | Lyophilized from a0.2 µm filtered concentrated solution in PBS, pH 7.4. |
Molecular Weight : | 14.4 kDa |
Sequence : | APARSPSPGTQPWEHVNAIQ EARRLLNLSR DTAAEMNKTV EVVSEMFDLQEPSCLQTRLE LYKQGLQGSL TKLKGPLTMMASHYKQHCPP TPETSCATQIITFQSFKENL KDFLLVIPFD CWEPVQE |
Purity : | > 98% by SDS-PAGEand HPLC analyses |
Biological Activity : | Fully biologicallyactive when compared to standard. The ED50 as calculated by the dose-dependant stimulation of the proliferation of human TF-1 cells is less than0.1 ng/ml, corresponding to a Specific Activity of 1.0×10⁷ IU/mg. |
Endotoxin Level : | < 0.1 ng/µg ofprotein |
Reconstitution : | Centrifuge vialprior to opening. Reconstitute in sterile distilled water or aqueous buffercontaining 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutionsshould be apportioned into working aliquots and stored at ≤-20°C. Further dilutionsshould be made in appropriate buffered solutions. |
Storage : | The lyophilizedprotein is stable at 2-4°C, but should be kept desiccated at -20°C for longterm storage. After reconstitution, the protein is stable for 1 week at2-4°C. For long term storage, aliquot and freeze at -80°C. Avoid repeatedfreeze-thaw cycles. |
OfficialSymbol : | CSF2 |
Gene Name : | CSF2 colony stimulating factor 2(granulocyte-macrophage) [ Macaca mulatta ] |
Synonyms : | CSF2; colony stimulating factor 2 (granulocyte-macrophage);GM-CSF |
Gene ID : | 574371 |
mRNA Refseq : | NM_001032949 |
Protein Refseq : | NP_001028121 |
Pathway : | Amoebiasis; CytokineSignaling in Immune system; Cytokine-cytokine receptor interaction; Fcepsilon RI signaling pathway; HTLV-I infection; Hematopoietic cell lineage;Interleukin-3, 5 and GM-CSF signaling; Jak-STAT signaling pathway; Naturalkiller cell mediated cytotoxicity; Rheumatoid arthritis; Salmonellainfection; T cell receptor signaling pathway |
Products Types
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◆ Lysates | ||
CSF2-1008MCL | Recombinant Mouse CSF2 cell lysate | +Inquiry |
CSF2-3008HCL | Recombinant Human CSF2 cell lysate | +Inquiry |
CSF2-740RCL | Recombinant Rat CSF2 cell lysate | +Inquiry |
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