"CSF3" Related Products

Recombinant Rhesus macaque CSF3

Cat.No.: CSF3-387R
Product Overview: Recombinant Rhesus macaque CSF3 was expressed in E.coli.
Description: Colony Stimulating Factor 3 (CSF3), previously known as granulocyte colony stimulating factor (G-CSF) is a pleiotropic cytokine and mainly produced by monocytes and macrophages upon activation by endotoxin, TNF-α and IFN-γ. Many cell types secreted this protein after LPS, IL-1 or TNFα activation, including fibroblasts, endothelial cells, astrocytes and bone marrow stromal cells. Various carcinoma cell lines and myeloblastic leukemia cells can express CSF3 constitutively. CSF3 is cytokine that acts in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytesmacrophages. In addition it may function in some adhesion or recognition events at the cell surface.
Source: E.coli
Species: Rhesus macaque
Form: Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.
Bio-activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine NFS-60 cells is less than 0.05 ng/ml, corresponding to a specific activity of >2.0×10^7 IU/mg.
Molecular Mass: ~18.9 kDa (174 amino acids)
Purity: >98% by SDS-PAGE and HPLC analyses.
Storage: Storage/Handling: Store desiccated at -20ºC.
Gene Name: CSF3 colony stimulating factor 3 (granulocyte) [ Macaca mulatta (Rhesus monkey) ]
Official Symbol: CSF3
Synonyms: CSF3; colony stimulating factor 3 (granulocyte)
Gene ID: 698961
mRNA Refseq: XM_001095097
Protein Refseq: XP_001095097
Chromosome Location: 16
Pathway: Cytokine-cytokine receptor interaction; Hematopoietic cell lineage; Jak-STAT signaling pathway

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