"DEFB4A" Related Products

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Recombinant Human Defensin, Beta 4A

Cat. No. : DEFB4A -5387H
Product Overview : Recombinant HumanDefensin beta 4 is a single, non-glycosylated polypeptide chain containing 50amino acids.
Description : DEFB4A also known as skin-antimicrobial peptide 1(SAP1) is a peptide that in humans is encoded by the DEFB4 (defensin, beta 4)gene. Human DEFB4A is a cysteine-rich cationic low molecularweight antimicrobial peptide recently discovered in lesional skin.
Source : E. coli
Species : Human
Form : Lyophilized from asterile filtered solution in 20 mM PBS, pH 7.4 + 130 mM NaCl.
Molecular Weight : 6.0 kDa
Purity : > 98% by HPLC andSDS-PAGE.
Endotoxin Level : < 0.1 ng/µg ofDefensin beta 4.
Biological Activity : Determined by itsability to chemoattract human monocytes using a concentration range of 0.1-50ng/mL.
Sequence : EFELDRICGYGTARCRKKCR SQEYRIGRCP NTYACCLRKW DESLLNRTKP
Reconstitution : Centrifuge vialprior to opening. Add sterile distilled water or aqueous buffer to a concentrationof 0.1-1.0 mg/mL. Further dilutions should be made in appropriate bufferedsolutions.
Storage : Stable at 2-8°C, butbest kept desiccated -20°C. Upon reconstitution, stable for up to 1 week at2-8°C. For longer term, store in working aliquots below -20°C. Avoid repeatedfreeze/thaw cycles.
OfficialSymbol : DEFB4A
PDB rendering basedon 1e4q. :

Gene Name : DEFB4A defensin, beta 4A [ Homosapiens ]
Synonyms : DEFB4A; defensin,beta 4A; BD-2; SAP1; DEFB2; DEFB4; HBD-2; DEFB-2; DEFB102; hBD-2;beta-defensin 4A; Skin-antimicrobial peptide 1; defensin, beta 2; defensin,beta 4; OTTHUMP00000159651; skin-antimicrobial peptide 1; Defensin, beta 2;Skin-antimicrobial peptide 1
Gene ID : 1673
mRNA Refseq : NM_004942
Protein Refseq : NP_004933
MIM : 602215
UniProt ID : O15263
Chromosome Location : 8p23.1

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