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Native Human Apolipoprotein H (beta-2-glycoprotein I)

Cat.No.: APOH-5365H
Product Overview: Native human APOH was expressed in Human plasma.
Description: APOH, also known asbeta2Glycoprotein-1 (B2GP-1) is a plasma glycoprotein that circulates at aconcentration of 200 ug/mL (4mM). B2GP-1 has been identified as a constituentof chylomicrons, very low density lipoproteins and high density lipoproteinsin Human plasma. It has also been demonstrated to bind phospholipids, heparinand platelets where it can modulate the activity of adenylate (19percent).Although the precise functions) are as yet unknown, B2GP-1 has been shown tointerfere with blood coagulation by competitively binding to phospholipidsexposed during cell activation or damage.
Source: Human plasma
Species: Human
Form: Liquid in 0.02MTris-HCI+0.3M NaCI, pH 7.3.
Molecular Mass: 48000
Purity: ≥95% by SDS-PAGEanalysis
Storage: When stored at -80°C product is stable for 3 years from date of delivery. Avoid repeated freeze-thawcycles.
Concentration: 1.0 mg/ml
Gene Name: APOH apolipoprotein H (beta-2-glycoprotein I) [ Homo sapiens ]
Official Symbol: APOH
Synonyms: APOH; apolipoprotein H (beta-2-glycoprotein I); B2G1; beta-2-glycoprotein 1; beta 2 glycoprotein I; BG; B2GPI; apo-H; beta(2)GPI; APC inhibitor; anticardiolipin cofactor; activated protein C-binding protein; B2GP1;
Gene ID: 350
mRNA Refseq: NM_000042
Protein Refseq: NP_000033
MIM: 138700
UniProt ID: P02749
Chromosome Location: 17q23-qter
Function: eukaryotic cell surface binding; glycoprotein binding; heparin binding; lipid binding; lipoprotein lipase activator activity; phospholipid binding; protein binding;

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