"PRKCB" Related Products


Recombinant Human Protein Kinase C, Beta, GST-tagged

Cat. No. : PRKCB-1302H
Product Overview : Recombinanthuman full length PRKCB with N-terminal GST tag was expressed in Sf9 insectcells.
Description : PRKCB isa member of the protein kinase C (PKC) family of serine- andthreonine-specific protein kinases that can be activated by calcium andsecond messenger diacylglycerol and phosphorylate a wide variety of proteintargets known to be involved in diverse cellular signaling pathways. PRKCBhas been reported to be involved in many different cellular functions such asB-cell activation, apoptosis induction, endothelial cell proliferation, andintestinal sugar absorption.
Source : Sf9 insect cells
Species : Human
Form : Liquid in50 mM Tris-HCl, pH 7.5 + 150 mM NaCl + 0.25 mM DTT + 0.1 mM EGTA + 0.1 mMEDTA + 0.1 mM PMSF + 25% glycerol.
Molecular Weight : ~ 150 kDa
Purity : > 90% asdetermined by densitometry
Concentration : 0.1 mg/ml
Specific Activity : 368nmol/min/mg
Storage : Stablefor 1 year in working aliquots at -80°C. Avoid repeated freeze-thaw cycles.
OfficialSymbol : PRKCB
nullValue_other :
Functionnucleotide binding; proteinbinding; protein kinase activity; protein serine/threonine kinase activity; zincion binding; metal ion binding; histone kinase activity (H3-T6 specific); enzymebinding; ATP binding
Rendering based onPDB 1a25. :

Gene Name : PRKCB protein kinase C, beta [ Homosapiens ]
Synonyms : PRKCB; proteinkinase C, beta; PKCB; PRKCB1; PRKCB2; MGC41878; PKC-beta; proteinkinase C, beta 1; OTTHUMP00000162377; OTTHUMP00000162378; Protein kinase C, betatype; PKC-B;EC; protein kinase C, beta 1 polypeptide
Gene ID : 5579
mRNA Refseq : NM_002738
Protein Refseq : NP_002729
MIM : 176970
UniProt ID : P05771
Chromosome Location : 16p12
Pathway : African trypanosomiasis; Aldosterone-regulatedsodium reabsorption; Alpha6-Beta4 Integrin Signaling Pathway; Amoebiasis; Ca-dependentevents; CaM pathway; Calcium Regulation in the Cardiac Cell; Calciumsignaling pathway; Calmodulin induced events; Canonical NF-kappaB pathway; Cholinergicsynapse; DAG and IP3 signaling; Disinhibition of SNARE formation; Dopaminergicsynapse

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