Recombinant Mouse Plasminogen Activator, Urokinase
Cat.No. : | Plau-1294M |
Product Overview : | Recombinant MouseLow Molecular Weight Urokinase Active. |
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- Gene Information
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Cat. No. : | Plau-1294M |
Description : | Plau encodes aserine protease involved in degradation of the extracellular matrix andpossibly tumor cell migration and proliferation. A specific polymorphism inthis gene may be associated with late-onset Alzheimer disease and also withdecreased affinity for fibrin-binding. Plau encoded by this gene convertsplasminogen to plasmin by specific cleavage of an Arg-Val bond inplasminogen. This gene"s proprotein is cleaved at a Lys-Ile bond by plasminto form a two-chain derivative in which a single disulfide bond connects theamino-terminal A-chain to the catalytically active, carboxy-terminal B-chain.This two-chain derivative is also called Plau. Plau can be further processedinto LMW- Plau (low molecular weight Plau) by cleavage of chain A into ashort chain A (A1) and an amino-terminal fragment. LMW- Plau isproteolytically active but does not bind to the Plau receptor. |
Source : | Insect cells |
Species : | Mouse |
Form : | Liquid in 0.05 Msodium acetate + 0.1 M NaCl + 1 mM EDTA, pH 5.0 |
Molecular Weight : | 31.0 kDa |
Concentration : | 2.0 mg/ml |
Storage : | Store in workingaliquots at -80°C. Avoid repeated freeze-thaw cycles. |
OfficialSymbol : | Plau |
Gene Name : | Plau plasminogen activator,urokinase [ Mus musculus ] |
Synonyms : | Plau; plasminogenactivator, urokinase; PA; u-PA; urokinase-type plasminogen activator;U-plasminogen activator; EC 3.4.21.73 |
Gene ID : | 18792 |
mRNA Refseq : | NM_008873 |
Protein Refseq : | NP_032899 |
UniProt ID : | P06869 |
Chromosome Location : | 14 A3; 14 2.5 cM |
Pathway : | Blood ClottingCascade; Complement and Coagulation Cascades; Dissolution of Fibrin Clot;Endochondral Ossification; Hemostasis; Wnt Signaling Pathway; Wnt SignalingPathway and Pluripotency |
Function : | catalytic activity;hydrolase activity; kinase activity; peptidase activity; serine-typeendopeptidase activity; serine-type peptidase activity |
Products Types
◆ Recombinant Protein | ||
PLAU-6811M | Recombinant Mouse PLAU Protein, His (Fc)-Avi-tagged | +Inquiry |
PLAU-1868H | Recombinant Human PLAU Protein, MYC/DDK-tagged | +Inquiry |
PLAU-391C | Recombinant Cattle PLAU Protein, His-tagged | +Inquiry |
Plau-4908M | Recombinant Mouse Plau Protein, Myc/DDK-tagged | +Inquiry |
PLAU-806H | Recombinant Human PLAU Protein | +Inquiry |
◆ Native Protein | ||
PLAU -14H | Native Human HMW urokinase, fluorescein labeled | +Inquiry |
PLAU-22H | Native Human PLAU protein | +Inquiry |
PLAU-31689TH | Active Native Human Urokinase protein | +Inquiry |
◆ Lysates | ||
PLAU-1734HCL | Recombinant Human PLAU cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0702 | PLAU (Human) Chromogenic Activity Assay Kit (Direct Assay) | +Inquiry |
Kit-0703 | PLAU (Human) Chromogenic Activity Assay Kit (Indirect Assay) | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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