Recombinant Human PAS Domain Containing Serine/Threonine Kinase, GST-tagged

• Cat.No.: PASK-1286H
• Product Overview: Recombinant humanPASK (amino acids 879-1323), N-terminal GST-tag, baculovirus insect cellexpression.

Specification

• Cat. No.: PASK-1286H
• Description: PASdomain-containing serine/threonine-protein kinase is an enzyme that in humansis encoded by the PASK gene. PAS domains regulate the function of manyintracellular signaling pathways in response to both extrinsic and intrinsicstimuli. PASK is an evolutionarily conserved protein present in yeast, flies,and mammals.
• Source: Insect cells
• Species: Human
• Form: Liquid in 50 mMTris, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2 mM DTT +50% glycerol.
• Concentration: 0.18 mg/ml totalprotein as measured using the Bradford protein assay with BSA as a standard.
• Purity: ≥ 70% as determinedby a Coomassie blue-stained SDS-PAGE gel
• Specific Activity: ≥ 50 nmol phosphatetransferred to Ribosomal S6 peptide substrate (AKRRRLSSLRA)/min/mg.
• Storage: Store at -80°C. Atfirst use, aliquot and store at -80°C to avoid multiple freeze-thaws. Ifproperly stored at -80°C, this product is guaranteed for 6 months from dateof purchase. This protein not stable at room temperature (activity decreasesby 50% after 8 hours). Stable for at least 48 hours at 2-4°C.
• OfficialSymbol: PASK

Gene Information

• Gene Name: PASK PAS domain containing serine/threoninekinase [ Homo sapiens ]
• Synonyms: PASK; PAS domaincontaining serine/threonine kinase; STK37; PASKIN; KIAA0135; DKFZp434O051;DKFZp686P2031; OTTHUMP00000200461; PAS-serine/threonine kinase; EC 2.7.11.1; hPASK;PAS-kinase
• Gene ID: 23178
• mRNA Refseq: NM_015148
• Protein Refseq: NP_055963
• MIM: 608038
• UniProt ID: Q96RG2
• Chromosome Location: 2q37.3
• Function: ATP binding; nucleotidebinding; protein serine/threonine kinase activity; signal transducer activity