"MYLK" Related Products

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Recombinant Human Myosin Light Chain Kinase, GST-tagged

Cat. No.: MYLK-696H
Product Overview: Recombinant humanMYLK catalytic domain (amino acids 1428-1771), GST-tagged.
Description: MYLK is a serine/threonine kinase thatphosphorylates myosin regulatory light chains to assist in the production ofcontractile activity (myosin-actin interaction). No special measures weretaken to activate this kinase.
Source: Insect cells
Species: Human
Form: Liquid in 50 mMTris, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2 mM DTT +50% glycerol.
Molecular Weight: 67.3 kDa
storage: Stablefor 6 months in working aliquots at -80°C. Avoidrepeated freeze-thaw cycles.
OfficialSymbol: MYLK
Pathways: Calcium signaling pathway;Focal adhesion; Regulation of actin cytoskeleton; Vascular smooth musclecontraction
Gene Name: MYLK myosin light chain kinase [Homo sapiens ]
Synonyms: MYLK; myosin light chainkinase; KRP; MLCK; MLCK1; MYLK1; smMLCK; MLCK108; MLCK210; MSTP083; FLJ12216;DKFZp686I10125; OTTHUMP00000180642; myosin, light polypeptide kinase; smoothmuscle myosin light chain kinase; EC 2.7.11.18; OTTHUMP00000180643; Telokin;smMLCK; Kinase-related protein; Myosin light chain kinase, smooth muscle
Gene ID: 4638
mRNA Refseq: NM_053025
Protein Refseq: NP_444253
MIM: 600922
UniProt ID: Q15746
Chromosome Location: 3q21
Function: ATP binding; actin binding;calcium ion binding; calmodulin binding; magnesium ion binding; myosin lightchain kinase activity; nucleotide binding; transferase activity

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