Recombinant Human Myosin Light Chain Kinase, GST-tagged

• Cat.No.: MYLK-696H
• Product Overview: Recombinant humanMYLK catalytic domain (amino acids 1428-1771), GST-tagged.

Specification

• Species: Human
• Source: Insect Cells
• Tag: GST
• Protein Length: 1428-1771 a.a.
• Description: MYLK is a serine/threonine kinase thatphosphorylates myosin regulatory light chains to assist in the production ofcontractile activity (myosin-actin interaction). No special measures weretaken to activate this kinase.
• Form: Liquid in 50 mMTris, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2 mM DTT +50% glycerol.
• Molecular Weight: 67.3 kDa
• storage: Stablefor 6 months in working aliquots at -80°C. Avoidrepeated freeze-thaw cycles.
• OfficialSymbol: MYLK
• Pathways: Calcium signaling pathway;Focal adhesion; Regulation of actin cytoskeleton; Vascular smooth musclecontraction

Gene Information

• Gene Name: MYLK myosin light chain kinase [Homo sapiens ]
• Synonyms: MYLK; myosin light chainkinase; KRP; MLCK; MLCK1; MYLK1; smMLCK; MLCK108; MLCK210; MSTP083; FLJ12216;DKFZp686I10125; OTTHUMP00000180642; myosin, light polypeptide kinase; smoothmuscle myosin light chain kinase; EC 2.7.11.18; OTTHUMP00000180643; Telokin;smMLCK; Kinase-related protein; Myosin light chain kinase, smooth muscle
• Gene ID: 4638
• mRNA Refseq: NM_053025
• Protein Refseq: NP_444253
• MIM: 600922
• UniProt ID: Q15746
• Chromosome Location: 3q21
• Function: ATP binding; actin binding;calcium ion binding; calmodulin binding; magnesium ion binding; myosin lightchain kinase activity; nucleotide binding; transferase activity