Recombinant Human Nuclear Factor Of Activated T-cells, Cytoplasmic, Calcineurin-Dependent 1, His-tagged
Cat.No. : | NFATC1-1274H |
Product Overview : | Recombinant humanNFATC1 contains amino acids 2-298 and N-terminal polyhistidine tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | NFATC1-1274H |
Description : | NFATC1 is a member of the NFATfamily of proteins which are Ca2+/calcineurin-responsivetranscription factors primarily recognized for their central roles in Tlymphocyte activation and cardiac valve development. NFAT consists of atleast two components: a preexisting cytosolic component that translocates tothe nucleus upon T-cell receptor (TCR) stimulation, and an inducible nuclearcomponent. |
Source : | E. coli |
Species : | Human |
Form : | Carrier-free liquid. |
Molecular Weight : | 35 kDa(migrates at ~ 48 kDa on SDS-PAGE gel) |
Purity : | 95% asdetermined by SDS-PAGE analysis |
Biological Activity : | Recombinanthuman NFATC1 is phosphorylatable in vitro,using recombinant GSK3 and PKA. Optimization of the cell stimulationprotocol, cell lysis procedure, and reaction conditions may be required foreach specific application. |
storage : | Store at2-4°C for short term storage. Stable for 1 year in working aliquots at -20°C.Avoid repeated freeze-thaw cycles. |
OfficialSymbol : | NFATC1 |
Pathways : | Axon guidance; B cell receptorsignaling pathway; Natural killer cell mediated cytotoxicity; T cell receptorsignaling pathway; VEGF signaling pathway; Wnt signaling pathway |
Gene Name : | NFATC1 nuclear factor ofactivated T-cells, cytoplasmic, calcineurin-dependent 1 [ Homo sapiens] |
Synonyms : | NFATC1; nuclear factor ofactivated T-cells, cytoplasmic, calcineurin-dependent 1; NFAT2; NFATc; NF-ATC;MGC138448; NFAT transcription complex cytosolic component; Nuclear factor ofactivated T-cells, cytoplasmic 1; NF-ATc1; NFATC; NFAT transcription complexcytosolic component |
Gene ID : | 4772 |
mRNA Refseq : | NM_006162 |
Protein Refseq : | NP_006153 |
MIM : | 600489 |
UniProt ID : | O95644 |
Chromosome Location : | 18q23 |
Function : | FK506 binding; promoter binding;protein binding; transcription activator activity; transcription factoractivity |
Products Types
◆ Recombinant Protein | ||
Nfatc1-4387M | Recombinant Mouse Nfatc1 Protein, Myc/DDK-tagged | +Inquiry |
Nfatc1-1823M | Recombinant Mouse Nfatc1 Protein, His-tagged | +Inquiry |
Nfatc1-1822M | Recombinant Mouse Nfatc1 Protein, His-tagged | +Inquiry |
NFATC1-7051H | Recombinant Human NFATC1, GST-tagged | +Inquiry |
NFATC1-29253TH | Recombinant Human NFATC1 | +Inquiry |
◆ Lysates | ||
NFATC1-3859HCL | Recombinant Human NFATC1 293 Cell Lysate | +Inquiry |
NFATC1-3858HCL | Recombinant Human NFATC1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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