"CTDSPL" Related Products

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Recombinant Human CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) Small Phosphatase-Like, His-tagged

Cat. No.: CTDSPL-1922H
Product Overview: Recombinant human CTDSPLprotein, fused to His-tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography.
Description: CTDSPL,also known as CTD small phosphatase-like protein, preferentially catalyzesthe dephosphorylation of Ser-5 within the tandem 7 residues repeats in theC-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A.
Form: Liquid. 20mMTris-HCl buffer (pH8.0) containing 40% glycerol, 0.15M NaCl, 1mM DTT.
Molecular Weight: 23.9 kDa(209aa) confirmed by MALDI-TOF
Purity: > 90%by SDS-PAGE
Concentration: 0.5mg/ml (determined by Bradford assay)
Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MGSHMKYLLP EVTVLDYGKK CVVIDLDETL VHSSFKPISN ADFIVPVEID GTIHQVYVLKRPHVDEFLQR MGQLFECVLF TASLAKYADP VADLLDRWGV FRARLFRESC VFHRGNYVKD LSRLGRELSKVIIVDNSPAS YIFHPENAVP VQSWFDDMTD TELLDLIPFF EGLSREDDVY SMLHRLCNR
Storage: Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways: BMPreceptor signaling; Regulation of cytoplasmic and nuclear SMAD2/3 signaling
Gene Name: CTDSPL CTD (carboxy-terminaldomain, RNA polymerase II, polypeptide A) small phosphatase-like [ Homosapiens ]
Official Symbol: CTDSPL
Synonyms: CTDSPL; CTD (carboxy-terminal domain, RNApolymerase II, polypeptide A) small phosphatase-like; PSR1; SCP3; HYA22;RBSP3; C3orf8; CTD small phosphatase-like protein; CTDSP-like;NIF-like protein; small CTD phosphatase 3; NLI-interacting factor 1; smallC-terminal domain phosphatase 3; nuclear LIM interactor-interacting factor 1;RB protein serine phosphatase from chromosome 3; carboxy-terminal domain RNApolymerase II polypeptide A small phosphatase 3; EC 3.1.3.16; chromosome3 open reading frame 8
Gene ID: 10217
mRNA Refseq: NM_001891
Protein Refseq: NP_001882
MIM: 608592
UniProt ID: O15194
Chromosome Location: 3p21.3
Function: hydrolase activity; metal ion binding;molecular function; phosphoprotein phosphatase activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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