Recombinant Human SENP1 Catalytic Domain, His-tagged
Cat.No. : | SENP1-688H |
Product Overview : | Recombinant, human SENP1 Catalytic Domain consistingof amino acids 415-643 was fused with a His Tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | SENP1-688H |
Description : | The covalent modification of proteins by SUMO is reversibleand is mediated by SENP enzymes. SENPs cleave residues from the C-terminus ofSUMO precursor proteins to generate the mature and active form which containsthe conserved C-terminal di-glycine. These enzymes also reverse the processof SUMOylation by removing poly-SUMO conjugates from substrate proteins.SENP1 is active against SUMO-1, SUMO-2 and SUMO-3 in vitro but not ubiquitinor NEDD8. |
MolecularWeight : | 29.8 kDa |
Stock : | In 50 mM Hepes pH 8.0, 100 mM NaCl, 10% glycerol, 5 mM DTT. |
Purity : | > 95% bySDS-PAGE |
Use : | Typical enzymeconcentration to support hydrolysis of substrates in vitro is 50-500 nM depending onconditions. Pre-incubation (15 min) with 10 mM DTT isrecommended toachieve maximum activity |
Storage : | Store at-80°C. Avoid multiple freeze/thaw cycles. |
Gene Name : | SENP1SUMO1/sentrin specific peptidase 1 [ Homo sapiens ] |
Official Symbol : | SENP1 |
Synonyms : | SENP1; SUMO1/sentrin specific peptidase 1; SuPr-2;sentrin-specific protease 1; SUMO1/sentrin specific protease 1;sentrin/SUMO-specific protease SENP1 |
Gene ID : | 29843 |
mRNA Refseq : | NM_014554 |
Protein Refseq : | NP_055369 |
MIM : | 612157 |
UniProt ID : | Q9P0U3 |
Chromosome Location : | 12q13.1 |
Pathway : | Androgen Receptor Signaling Pathway; Regulationof Androgen receptor activity |
Function : | cysteine-typepeptidase activity; endopeptidase activity; peptidase activity |
Products Types
◆ Recombinant Protein | ||
SENP1-8013M | Recombinant Mouse SENP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
SENP1-180H | Recombinant Human SENP1, His-tagged | +Inquiry |
SENP1-14878M | Recombinant Mouse SENP1 Protein | +Inquiry |
SENP1-687H | Recombinant Human SENP1, His-tagged | +Inquiry |
SENP1-686H | Active Recombinant Human SENP1, GST-tagged | +Inquiry |
◆ Lysates | ||
SENP1-1975HCL | Recombinant Human SENP1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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