Active Recombinant Mouse Intercellular Adhesion Molecule 1, Fc-tagged
Cat.No. : | Icam1-5640M |
Product Overview : | RecombinantMouse Icam1 protein was expressed in Murine myeloma cell line with the Fcpart of Human IgG1 Pro100-Lys330 (C-terminus) and Mouse Icam1 Gln28-Asn485(N-terminus). |
- Specification
- Gene Information
- Related Products
Cat. No. : | Icam1-5640M |
Description : | Icam1binds the leukocyte integrins LFA-1 and Mac-1. Icam1 expression is weak onleukocytes, epithelial and resting endothelial cells, as well as some othercell types, but expression can be stimulated by IFN-γ, TNF-α, IL-1β and LPS.Mouse and human Icam1 share approximately 54% amino acid identity. |
Source : | Mammalian cells |
Form : | Lyophilizedfrom a 0.2 um filtered solution in PBS. |
N-terminalSequence : | Gln28 |
MolecularWeight : | 76.8 kDa (monomer) |
Activity : | Measuredby the ability of the immobilized protein to support the adhesion ofPMA-stimulated HSB2 human peripheral blood acute lymphoblastic leukemiacells. When 5x104cells/well are added to rmICAM/Fc Chimera coatedplates (12.5 μg/Ml with 100 μL/well), approximately 65-95% will adhere after1 hour incubation at 37°C. |
Endotoxin Level : | <1.0EU per 1μg of the protein by the LAL method. |
SDS-PAGE : | 110-130kDa, reducing conditions. |
Purity : | >95%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Reconstitution : | 0.4 mg/mLin sterile PBS |
Storage : | Use a manual defrostfreezer and avoid repeated freeze-thaw cycles. 12 months from dateof receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterileconditions after reconstitution. 3 months, -20 to -70°C under sterileconditions after reconstitution. |
Gene Name : | Icam1 intercellular adhesionmolecule 1 [ Mus musculus ] |
Official Symbol : | Icam1 |
Synonyms : | Icam1; intercellularadhesion molecule 1; CD54; Ly-47; Icam-1; MALA-2; myD10; Intercellular adhesion molecule |
Gene ID : | 15894 |
mRNA Refseq : | NM_010493 |
Protein Refseq : | NP_034623 |
UniProt ID : | Q3U8M7 |
Chromosome Location : | 9 |
Pathway : | Adaptive ImmuneSystem; African trypanosomiasis; Cell adhesion molecules (CAMs); HTLV-Iinfection; IL-2 Signaling Pathway; IL-5 Signaling Pathway; Immune System; InfluenzaA; Integrin cell surface interactions; Leukocyte transendothelial migration; Malaria;Natural killer cell mediated cytotoxicity; PluriNetWork; Rheumatoid arthritis;Signal Transduction |
Function : | cell surface binding;integrin binding; protein complex binding |
Products Types
◆ Recombinant Protein | ||
Icam1-58M | Recombinant Mouse Icam1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ICAM1-22H | Recombinant Human ICAM1 Protein, Fc-His-tagged | +Inquiry |
ICAM1-2005R | Recombinant Rhesus Macaque ICAM1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ICAM1-2266R | Recombinant Rabbit ICAM1 Protein, His&SUMO-tagged | +Inquiry |
Icam1-3323M | Active Recombinant Mouse Icam1 protein(Met1-Asn485), His&hFc-tagged | +Inquiry |
◆ Lysates | ||
ICAM1-2487MCL | Recombinant Mouse ICAM1 cell lysate | +Inquiry |
ICAM1-2655HCL | Recombinant Human ICAM1 cell lysate | +Inquiry |
ICAM1-1970RCL | Recombinant Rat ICAM1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket