"FUT3" Related Products

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Recombinant Human Fucosyltransferase 3 (galactoside 3 (4)-L-fucosyltransferase, Lewis blood group), His-tagged

Cat. No.: FUT3-573H
Product Overview: Recombinanthuman FUT3 protein was expressed in Murine myeloma cell line, NS0-derived,with an N-terminus 6-His tag. Arg35-Thr361.
Description: FUT3 is often foundto be essential for sugar epitope and lectin ligand generation. Well knownFUT3 containing structures include Lewis structures and ABO blood groupantigens. Lewis structures are key elements involved in leukocyte homing and extravasationprocess and thus are essential for lymphocyte maturation and natural defense functions.
Source: Murine myeloma cellline, NS0-derived
Form: Supplied as a 0.2 μmfiltered solution in Tris and NaCl.
N-terminal Sequence: His
Molecular Weight: 39 kDa
Activity: Measured by itsability to transfer fucose from GDP-fucose to N-Acetyllactosamine. Thespecific activity is > 25 pmol/min/μg, as measured under the described conditions.
Endotoxin Level: <1.0 EU per 1 μgof the protein by the LAL method.
SDS-PAGE: 41 kDa, reducingconditions
Purity: >90%, by SDS-PAGEunder reducing conditions and visualized by silver stain.
Storage: Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3months, -20 to -70 °C under sterile conditions after reconstitution.
Gene Name: FUT3 fucosyltransferase 3(galactoside 3(4)-L-fucosyltransferase, Lewis blood group) [ Homo sapiens]
Official Symbol: FUT3
Synonyms: FUT3;fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis bloodgroup); fucosyltransferase 3 (galactoside 3(4) L fucosyltransferase, Lewisblood group included); LE; galactoside 3(4)-L-fucosyltransferase; CD174;MGC131739; alpha (1,3/1,4) fucosyltransferase; Blood group Lewisalpha-4-fucosyltransferase; FT3B; Fucosyltransferase 3; FucosyltransferaseIII; FucT-III; FUT3_HUMAN; galactoside 3(4) L fucosyltransferase, Lewis bloodgroup; Galactoside 3(4)-L-fucosyltransferase; Lewis B Blood Group antigen;Lewis FT; alpha-(1,3/1,4)-fucosyltransferase; Les
Gene ID: 2525
mRNA Refseq: NM_000149
Protein Refseq: NP_000140
MIM: 111100
UniProt ID: P21217
Chromosome Location: 19p13.3
Pathway: Glycosphingolipidbiosynthesis-lacto and neolacto series; Metabolic pathways
Function: 3-galactosyl-N-acetylglucosaminide4-alpha-L-fucosyltransferase activity; alpha-(1->3)-fucosyltransferaseactivity; fucosyltransferase activity; transferase activity, transferringglycosyl groups

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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