"HYAL4" Related Products


Recombinant Human Hyaluronoglucosaminidase 4, His-tagged

Cat. No.: HYAL4-1973H
Product Overview: RecombinantHuman HYAL4 protein was expressed in Chinese HamsterOvary cell line. Cys34-Pro462, with an N-terminal CD33signals sequence and a C-terminal 6-His tag.
Description: Humanhyaluronidases (HYALs) are a group of five endoβ-N-acetyl-hexosaminidases thatinclude HYAL1, HYAL2, HYAL3, HYAL4, and SPAM1 (PH20). While HYAL1, HYAL2 andSPAM1 are endoβ-N-acetyl-glucosaminidase that are mainly active on hyaluronanwith little activity on chondroitin sulfate, HYAL4 is the only known endoβ-N-acetyl-galactosaminidasethat is mainly active on chondroitin sulfate (type C and D in particular)with no activity on hyaluronan. Hyaluronan and chondroitin sulfate areabundant extracellular matrix components that have numerous biologicalfunctions.
Source: Chinese HamsterOvary cell line, CHO-derived.
Form: Supplied as a 0.2 μmfiltered solution in Tris, NaCl and Glycerol.
N-terminalSequence: Cys34
MolecularWeight: 49 kDa
Activity: Measuredby its ability to hydrolyze S-35 labeled bovine cartilage chondroitin sulfate< 500 ng of rhHYAL4 is required for the 50% hydrolysis of 10 μgchondroitin sulfate, as measured under the described conditions.
Endotoxin Level: <1.0EU per 1μg of the protein by the LAL method.
SDS-PAGE: 66-85kDa, reducing conditions.
Purity: >95%,by SDS-PAGE under reducing conditions and visualized by Colloidal CoomassieBlue stain at 5 ug per lane.
Storage: Use amanual defrost freezer and avoid repeated freezethaw cycles. 6 monthsfrom date of receipt, -20 to -70°C as supplied. 3 months,-20to-70°C under sterile conditions after opening.
Gene Name: HYAL4 hyaluronoglucosaminidase4 [ Homo sapiens ]
Official Symbol: HYAL4
Synonyms: HYAL4;hyaluronoglucosaminidase 4; CSHY; hyaluronidase-4;hyal-4; hyaluronidase 4; hyaluronoglucosaminidase-4;chondroitin sulfate hydrolase; EC
Gene ID: 23553
mRNA Refseq: NM_012269
Protein Refseq: NP_036401
MIM: 604510
UniProt ID: Q2M3T9
Chromosome Location: 7q31.3
Pathway: Chondroitin sulfate degradation; Dermatansulfate degradation; Glycosaminoglycan degradation; Metabolic pathways
Function: hyalurononglucosaminidaseactivity; hydrolase activity, acting on glycosyl bonds

Online Inquiry

Note: There will be extra charge for optional service!
Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Price does not include shipping and packaging costs.Request quote for final price.

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.