"Klk5" Related Products

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Recombinant Mouse Kallikrein Related-Peptidase 5, His-tagged

Cat. No.: Klk5-1978M
Product Overview: RecombinantMouse Klk5 protein was expressed in Murine myeloma cell line. Val23-Asn293,with an N-terminal human CD33 signal peptide and a C-terminal 10-His tag.
Description: Klk5 is asecreted serine protease with trypsinlike substrate specificity. Klk5 ishighly expressed in the skin, and is also known as stratum corneum trypticenzyme due to its high expression level in this tissue. Klk5 isthought to play an important role in the process of desquamation. Klk5 is apotential biomarker for ovarian and breast cancers. It may also be a physiologicalactivator of KLK7 in the stratum corneum. Recombinant mouse Klk5 ispurified as the proform, and can undergo autoactivation under the appropriateconditions.
Source: Murine myeloma cellline, NS0-derived.
Form: Supplied as a 0.2 umfiltered solution in Sodium Acetate, NaCl and Glycerol.
N-terminalSequence: Val23
MolecularWeight: 31 kDa
Activity: Measuredby its ability to cleave the fluorogenic peptide substrate Boc-VPR-AMC. Thespecific activity is > 1,350 pmol/min/μg, as measured under the described conditions.
Endotoxin Level: <1.0EU per 1μg of the protein by the LAL method.
SDS-PAGE: 40-50kDa, reducing conditions.
Purity: >95%,by SDS-PAGE under reducing conditions and visualized by Colloidal CoomassieBlue stain at 5 μg per lane.
Storage: Use a manual defrost freezer and avoid repeated freezethawcycles. 6months from date of receipt, -20 to -70°C as supplied. 3 months, -20 to -70°Cunder sterile conditions after opening.
Gene Name: Klk5 kallikreinrelated-peptidase 5 [ Mus musculus ]
Official Symbol: Klk5
Synonyms: Klk5; kallikreinrelated-peptidase 5; 1110030O19Rik; kallikrein-5; kallikrein 5
Gene ID: 68668
mRNA Refseq: NM_026806
Protein Refseq: NP_081082
UniProt ID: Q9D140
Chromosome Location: 7
Function: hydrolase activity;peptidase activity; serine-type endopeptidase activity; serine-type peptidaseactivity

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