"Alpl" Related Products

Expand
Expand

Recombinant Mouse Alkaline Phosphatase, Liver/Bone/Kidney, His-tagged

Cat. No.: Alpl-444M
Product Overview: Recombinant Mouse Alplprotein was expressed in Murine myeloma cell line. Phe18-Gly503, witha C terminal 6 His tag.
Description: Severaldistinct genes encode alkaline phosphatases (APs) in mice with differenttissuespecific expression patterns. The Alpl gene, also known as Akp2,encodes the liver/bone/kidney isozyme, also known as the tissuenonspecific AP(TNAP). The Alpl gene is a key regulator of bone mineralization in mice. Avariety of mutations in the human Alpl gene leads todifferent forms of hypophosphatasia, characterized by poorly mineralizedcartilage and bones.
Source: Murinemyeloma cell line, NS0-derived.
Form: Suppliedas a 0.2 um filtered solution in Tris and NaCl.
N-terminalSequence: Phe18
MolecularWeight: 54 kDa
Activity: Measuredby its ability to cleave a fluorogenic substrate, 4Methylumbelliferyl phosphate(4MUP). The specific activity is > 40000 pmoles/min/μg, as measured underthe described conditions. See Activity Assay Protocol.
Endotoxin Level: <1.0EU per 1 μg of the protein by the LAL method.
Purity: >95%,by SDSPAGE under reducing conditions and visualized by silver stain.
Storage: Do notfreeze. 3months from date of receipt, 2 to 8°C as supplied. 1 month, 2 to 8°C understerile conditions after opening.
Gene Name: Alpl alkaline phosphatase,liver/bone/kidney [ Mus musculus ]
Official Symbol: Alpl
Synonyms: Alpl; alkalinephosphatase, liver/bone/kidney; Akp2; TNAP; Akp-2; APTNAP; TNSALP; alkalinephosphatase, tissue-nonspecific isozyme; alkaline phosphatase 2, liver; EC 3.1.3.1
Gene ID: 11647
mRNA Refseq: NM_007431
Protein Refseq: NP_031457
UniProt ID: P09242
Chromosome Location: 4
Pathway: Endochondral Ossification;Folate biosynthesis; Metabolic pathways; TNF-alpha NF-kB Signaling Pathway
Function: alkaline phosphataseactivity; catalytic activity; hydrolase activity; metal ion binding; phosphataseactivity

Online Inquiry

Note: There will be extra charge for optional service!
Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information


Price does not include shipping and packaging costs.Request quote for final price.

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.