"Cxcl5" Related Products

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Recombinant Rat Chemokine (C-X-C motif) Ligand 5

Cat. No.: Cxcl5-445R
Product Overview: RecombinantRat Cxcl5 protein was expressed in E. coli. Ala38-Arg125& Ala38-Lys117.
Description: Cxcl5 is a chemokine originallycloned from LPS stimulated mouse fibroblasts. Rat Cxcl5 sharesapproximately 74% amino acid (aa) sequence identity with mouse Cxcl5 and islikely the rat orthologue to mouse Cxcl5. Rat Cxcl5 cDNAencodes a 130 aa residue precursor with a predicted 37 aa residue signalpeptide and a 93 aa residue mature protein. Among human CXC chemokines, rat Cxcl5 is mostclosely related to human GCP2 and ENA78. Rat Cxcl5 alsodiffers from these two human proteins by having an extended carboxyterminus.
Source: E. coli
Form: Lyophilized from a0.2 um filtered solution in Acetonitrile and TFA with BSA as a carrierprotein.
N-terminalSequence: Ala38
MolecularWeight: 10.1 kDa
Activity: Measuredby its ability to chemoattract human CXCR2 transfected BaF3 mouse proB cells.The ED50 for this effect is typically 0.03 0.15 μg/mL.
Endotoxin Level: <1.0EU per 1 μg of the protein by the LAL method.
Purity: >97%,by SDSPAGE under reducing conditions and visualized by silver stain.
Reconstitution: Reconstituteat 100μg/mL insterile PBS containing at least 0.1% human or bovine serum albumin.
Storage: Use amanual defrost freezer and avoid repeated freezethaw cycles. 12 months from date ofreceipt, 20 to 70°C as supplied. 1 month, 2 to 8°C under sterileconditions after reconstitution. 3 months, 20 to 70°C under sterileconditions after reconstitution.
Gene Name: Cxcl5 chemokine (C-X-C motif)ligand 5 [ Rattus norvegicus ]
Official Symbol: Cxcl5
Synonyms: Cxcl5; chemokine(C-X-C motif) ligand 5; Cxcl6; C-X-C motif chemokine 5; cytokineLIX; CXC chemokine LIX; small-inducible cytokine B5; chemokine (C-X-C motif)ligand 6 (granulocyte chemotactic protein 2)
Gene ID: 60665
mRNA Refseq: NM_022214
Protein Refseq: NP_071550
UniProt ID: P97885
Chromosome Location: 14
Pathway: Chemokine receptorsbind chemokines; Chemokine signaling pathway; Class A/1 (Rhodopsin-likereceptors); G alpha (i) signalling events; GPCR downstream signaling; GPCRligand binding; Peptide ligand-binding receptors; Pertussis; Rheumatoidarthritis; Signal Transduction; Signaling by GPCR
Function: chemokine activity

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