Recombinant Human Nicotinamide Riboside Kinase 1 Isoform 1, His-tagged
| Cat.No. : | NRK1-6793H |
| Product Overview : | Recombinant humanNRK1 protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography techniques. |
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- Gene Information
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| Cat. No. : | NRK1-6793H |
| Description : | NRK1 belongs to theuridine kinase family. NAD+ is essential for life in all organisms, both as acoenzyme for oxidoreductases and as a source of ADPribosyl groups used invarious reactions, including those that retard aging in experimental systems.Nicotinic acid and nicotinamide were defined as the vitamin precursors ofNAD+. This enzyme catalyzes the phosphorylation of nicotinamide riboside (NR)and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN)and nicotinic acid mononucleotide (NaMN). The enzyme also phosphorylates theantitumor drugs tiazofurin and 3-deazaguanosine |
| Form : | Liquid. In 20 mMTris-HCl buffer, pH8.0, 10% glycerol, 2mM DTT, 200mM NaCl |
| Molecular Weight : | 25.6kDa (222aa),confirmed by MALDI-TOF |
| Purity : | > 90% by SDS -PAGE |
| Concentration : | 0.5mg/ml (determinedby Bradford assay) |
| Sequences of aminoacids : | MGSSHHHHHHSSGLVPRGSH MGSMKTFIIG ISGVTNSGKT TLAKNLQKHL PNCSVISQDD FFKPESEIET DKNGFLQYDVLEALNMEKMM SAISCWMESA RHSVVSTDQE SAEEIPILII EGFLLFNYKP LDTIWNRSYF LTIPYEECKRRRSTRVYQPP DSPGYFDGHV WPMYLKYRQE MQDITWEVVY LDGTKSEEDL FLQVYEDLIQ ELAKQKCLQVTA |
| Storage : | Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles. |
| Gene Name : | C9orf95 chromosome 9 openreading frame 95 [Homo sapiens] |
| Official symbol : | C9orf95 |
| Synonyms : | chromosome9 open reading frame 95; Ribosylnicotinic acid kinase 1; FLJ20559; NRK 1;NRK1; RNK 1; bA235O14.2; OTTHUMP00000021494; Nicotinic acid riboside kinase1; nicotinamide riboside kinase 1; NmR-K 1; EC 2.7.1.22; Ribosylnicotinamidekinase 1; EC 2.7.1.n4; RP11-235O14.2; OTTHUMP00000021493; OTTHUMP00000021495 |
| Gene ID : | 54981 |
| mRNA Refseq : | NM_017881 |
| Protein Refseq : | NP_060351 |
| MIM : | 608704 |
| Uniprot ID : | Q9NWW6 |
| Chromosome Location : | 9q21.13 |
| Pathway : | Nicotinate and nicotinamide metabolism, organism-specificbiosystem; Nicotinate and nicotinamide metabolism, conserved biosystem |
| Function : | ATPbinding; metal ion binding; nucleotide binding; ribosylnicotinamide kinaseactivity; transferase activity |
Products Types
| ◆ Recombinant Protein | ||
| Nrk1-4435M | Recombinant Mouse Nrk1 protein, His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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