Recombinant Human Aldehyde Dehydrogenase 1 Family, Member L1, His-tagged

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Recombinant Human Aldehyde Dehydrogenase 1 Family, Member L1, His-tagged

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Cat. No. : ALDH1L1-491H
Product Overview : Recombinant Human ALDH1L1protein was expressed as 6-his-tagged fusion protein by E. coli and purifiedby Ni-sepharose. The purified protein was resolved in 1M PBS (58mMNa2HPO4,17mM NaH2PO4, 68mM NaCl, pH8.) added with 300mM Imidazole and 0.7% Sarcosyl,15%glycerol. MW= 44 kDa.
Description : ALDH1L1 encoded bythis gene catalyzes the conversion of 10-formyltetrahydrofolate, NADP, andwater to tetrahydrofolate, NADPH, and carbon dioxide. ALDH1L1 belongs to thealdehyde dehydrogenase family and is responsible for formate oxidation invivo. Deficiencies in ALDH1L1 can result in an accumulation of formate andsubsequent methanol poisoning.
Host : E. coli
Antigen peptideregion : 157-505aa
Molecular Weight : 44 kDa
Full length : False
Storage : Theprotein is stored in PBS buffer at -20°C.Repeated freeze-thaw cycles should be avoided.
Gene Name : ALDH1L1 aldehyde dehydrogenase1 family, member L1 [ Homo sapiens ]
Official Symbol : ALDH1L1
Synonyms : ALDH1L1;aldehyde dehydrogenase 1 family, member L1; FDH; FTHFD; 10-fTHF; cytosolic10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; formyltetrahydrofolatedehydrogenase; 10-formyltetrahydrofolate dehydrogenase; aldehydedehydrogenase family 1 member L1; EC 1.5.1.6; DKFZp781N0997;OTTHUMP00000155221; OTTHUMP00000214696; OTTHUMP00000214700;OTTHUMP00000222724
Gene ID : 10840
mRNA Refseq : NM_012190
Protein Refseq : NP_036322
MIM : 600249
UniProt ID : O75891
Chromosome Location : 3q21.3
Pathway : One CarbonMetabolism; One carbon pool by folate
Function : acyl carrieractivity; catalytic activity; cofactor binding; formyltetrahydrofolatedehydrogenase activity; hydroxymethyl-, formyl- and related transferaseactivity; methyltransferase activity; oxidoreductase activity; oxidoreductaseactivity, acting on the aldehyde or oxo group of donors, NAD or NADP asacceptor
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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