Recombinant Human Aldehyde Dehydrogenase 8 Family, Member A1, His-tagged

• Cat.No.: ALDH8A1-503H
• Product Overview: Recombinant Human ALDH8A1protein was expressed as 6-his-tagged fusion protein by E. coli and puried byNi-sepharose. The puried protein was resolved in 1M P BS (58mM Na2HP O4,17mMNaH2P O4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl,15%glycerol. MW=44 kDa.

Specification

• Cat. No.: ALDH8A1-503H
• Description: ALDH8A1 belongs tothe aldehyde dehydrogenase family of proteins. It plays a role in a pathwayof 9-cis-retinoic acid biosynthesis in vivo. ALDH8A1 converts 9-cis-retinalinto the retinoid X receptor ligand 9-cis-retinoic acid, and hasapproximately 40-fold higher activity with 9-cis-retinal than withall-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase toshow a preference for 9-cis-retinal relative to all-trans-retinal. Twotranscript variants encoding distinct isoforms have been identified for thisgene.
• Host: E. coli
• Antigen peptideregion: C-352aa
• Molecular Weight: 44 kDa
• Full length: False
• Storage: Theprotein is stored in PBS buffer at -20°C.Repeated freeze-thaw cycles should be avoided.

Gene Information

• Gene Name: ALDH8A1 aldehyde dehydrogenase8 family, member A1 [ Homo sapiens ]
• Official Symbol: ALDH8A1
• Synonyms: ALDH8A1;aldehyde dehydrogenase 8 family, member A1; ALDH12; DKFZp779D2315; MGC138650;DJ352A20.2; aldehyde dehydrogenase family 8 member A1; aldehyde dehydrogenase12; aldehyde dehydrogenase family protein; EC 1.2.1.-; EC 1.2.1; EC 1.2.1.3;OTTHUMP00000017250; OTTHUMP00000017251; OTTHUMP00000234165
• Gene ID: 64577
• mRNA Refseq: NM_022568
• Protein Refseq: NP_072090
• MIM: 606467
• UniProt ID: Q9H2A2
• Chromosome Location: 6q23.2
• Function: oxidoreductaseactivity; retinal dehydrogenase activity