Recombinant Human Aldehyde Dehydrogenase 8 Family, Member A1, His-tagged ALDH8A1-503H

Recombinant Human Aldehyde Dehydrogenase 8 Family, Member A1, His-tagged

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Recombinant Human Aldehyde Dehydrogenase 8 Family, Member A1, His-tagged

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Cat. No. : ALDH8A1-503H
Product Overview : Recombinant Human ALDH8A1protein was expressed as 6-his-tagged fusion protein by E. coli and puried byNi-sepharose. The puried protein was resolved in 1M P BS (58mM Na2HP O4,17mMNaH2P O4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl,15%glycerol. MW=44 kDa.
Description : ALDH8A1 belongs tothe aldehyde dehydrogenase family of proteins. It plays a role in a pathwayof 9-cis-retinoic acid biosynthesis in vivo. ALDH8A1 converts 9-cis-retinalinto the retinoid X receptor ligand 9-cis-retinoic acid, and hasapproximately 40-fold higher activity with 9-cis-retinal than withall-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase toshow a preference for 9-cis-retinal relative to all-trans-retinal. Twotranscript variants encoding distinct isoforms have been identified for thisgene.
Host : E. coli
Antigen peptideregion : C-352aa
Molecular Weight : 44 kDa
Full length : False
Storage : Theprotein is stored in PBS buffer at -20°C.Repeated freeze-thaw cycles should be avoided.
Gene Name : ALDH8A1 aldehyde dehydrogenase8 family, member A1 [ Homo sapiens ]
Official Symbol : ALDH8A1
Synonyms : ALDH8A1;aldehyde dehydrogenase 8 family, member A1; ALDH12; DKFZp779D2315; MGC138650;DJ352A20.2; aldehyde dehydrogenase family 8 member A1; aldehyde dehydrogenase12; aldehyde dehydrogenase family protein; EC 1.2.1.-; EC 1.2.1; EC 1.2.1.3;OTTHUMP00000017250; OTTHUMP00000017251; OTTHUMP00000234165
Gene ID : 64577
mRNA Refseq : NM_022568
Protein Refseq : NP_072090
MIM : 606467
UniProt ID : Q9H2A2
Chromosome Location : 6q23.2
Function : oxidoreductaseactivity; retinal dehydrogenase activity

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